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Neurological Research Compounds

Compounds used in neurological, neuronal and neurodegenerative disease research.

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Structure
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HY-W166106Bromoriluzole 144631-82-3 Bromoriluzole is a derivative of Riluzole ( HY-B0211 ). Bromoriluzole inhibits Ca 2+ -dependent Calmodulin - SK4...
HY-12131DMP 696 202578-52-7 DMP 696 is a selective corticotropin-releasing hormone receptor 1 (CRHR1) antagonist, used for the treatment of...
HY-121235Clonixin 17737-65-4 Clonixin (SCH-10304) is an orally active non-steroidal anti-inflammatory agent (NSAID) that inhibits COX synthesis....
HY-121141Adiphenine 64-95-9 Adiphenine is a non-competitive inhibitor of nicotinic acetylcholine receptor ( nAChR ) , with an IC 50 s of 1.9...
HY-120994BSp-8-CPT-cAMPS 129693-13-6 Sp-8-CPT-cAMPS, a cAMP analog, is a potent and selective activator of the cAMP-dependent protein kinas A ( PKA I and...
HY-120994ARp-8-CPT-cAMPS 129735-01-9 Rp-8-CPT-cAMPS, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent...
HY-120939S14063 137289-83-9 S14063 is a potent 5-HT1A receptor antagonist. S14063 is devoid of β-adrenoceptor blocking properties.
HY-120938JYL-273 analog-1 289902-71-2 JYL-273 analog-1 (Compound 28, Example 45) is a potent transient receptor potential ion channel ( TRP channel )...
HY-120928S 16474 149250-10-2 S 16474 is a cyclic peptide with antagonistic effects on NK1 and NK2 receptors. S 16474 can be used in the study of...
HY-120926BBR 2160 118587-22-7 BBR 2160 is a compound with cardiac electrophysiological effects and is a dihydropyridine calcium antagonist that...
HY-120837PZ-II-029 164025-44-9 PZ-II-029 is a GABAA positive allosteric modulator that selectively binds with high affinity to α6β3γ2 . PZ-II-029...
HY-120820LY320954 182633-59-6 LY320954 is a selective 5-HT2A receptor antagonist, with a K i of 96 nM. LY320954 potently inhibits Ca 2+ influx in...
HY-120741PF-04822163 1798334-07-2 PF-04822163 is an orally active, selective, and blood-brain barrier permeable PDE1 inhibitor with IC 50 values of 2...
HY-120691AGSK205 1263068-83-2 GSK205 is a potent, selective TRPV4 antagonist with an IC 50 of 4.19 μM for inhibiting TRPV4 -mediated Ca 2+ influx.
HY-120576ML169 1222878-02-5 ML169 (VU0405652) is a potent, selective and brain penetrant positive allosteric modulator (PAM) of M 1 mAChR , with...
HY-120481JNJ-40413269 1184847-16-2 JNJ-40413269 is an inhibitor for FAAH , that inhibits human FAAH and rats FAAH with IC 50 of 28 nM and 270 nM....
HY-120428VU0410425 1341167-72-3 VU0410425 is an mGlu 1 negative allosteric modulator. VU0410425 exhibits potent inhibitory activity for rat mGlu 1...
HY-120408(±)-Scopolamine 138-12-5 (±)-Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±)-Scopolamine inhibits α-adrenergic...
HY-120381PD 136450 139067-52-0 PD 136450 (CAM 1189) is an antagonist for cholecystokinin 2 ( CCK2 ). PD 136450 exhibits anti-secretory, anxiolytic...
HY-120369URB532 195140-79-5 URB532 is an inhibitor for fatty acid amide hydrolase ( FAAH ) with an IC 50 of 396 nM. URB532 increases levels of...

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