4-Methylsulfonylaniline

4-Methylsulfonylaniline
  • CAS No.:5470-49-5

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
4-Methylsulfonylaniline Basic information
Product Name:4-Methylsulfonylaniline
Synonyms:-(Methylsulfonyl)aniline;Benzenamine, 4-(methylsulfonyl)-;niline, p-(methylsulfonyl)-;4-(METHYLSULPHONYL)ANILINE;4-(METHYLSULFONYL)ANILINE;4-METHYLSULFONYL-BENZENEAMINE;4-mesylaniline;BENZENEAMINE, 4-METHYLSULFONYL-
CAS:5470-49-5
MF:C7H9NO2S
MW:171.22
EINECS:226-803-8
Product Categories:
Mol File:5470-49-5.mol
4-Methylsulfonylaniline Chemical Properties
Melting point 243-245°C
Boiling point 384.3±34.0 °C(Predicted)
density 1.44
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated)
form Crystalline Powder
pkapK1:1.48(+1) (25°C)
color White
Water Solubility Soluble in water.
Sensitive Light Sensitive
CAS DataBase Reference5470-49-5(CAS DataBase Reference)
NIST Chemistry Reference4-Aminophenyl methyl sufhone(5470-49-5)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-22
Safety Statements 22-24/25
Hazard Note Irritant
HazardClass 6.1
HS Code 2930909899
MSDS Information
ProviderLanguage
4-Mesylaniline English
4-Methylsulfonylaniline Usage And Synthesis
UsesIt is used as pharmaceutical intermediate. A series of 4-(methylsulfonyl)aniline derivatives were synthesized in order to obtain new compounds as a potential anti-inflammatory agents with expected selectivity against COX-2 enzyme.
Synthesis Reference(s)Tetrahedron Letters, 35, p. 7867, 1994 DOI: 10.1016/0040-4039(94)80139-8
4-Methylsulfonylaniline Preparation Products And Raw materials
Preparation Products4-(Methylsulfonyl)phenylhydrazine hydrochloride-->4-Bromophenyl methyl sulfone

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