Other grades of this product :
| 4-Bromoaniline Basic information |
| 4-Bromoaniline Chemical Properties |
| Melting point | 56-62 °C (lit.) | | Boiling point | 230-250 °C | | density | 1.497 | | refractive index | 1.5680 (estimate) | | Fp | 222-224°C | | storage temp. | Store below +30°C. | | solubility | ethanol: soluble0.5g/10 mL, clear, colorless to almost colorless | | form | crystalline | | pka | 3.86(at 25℃) | | color | white to light yellow | | Odor | Sweetish | | Water Solubility | <0.1 g/100 mL at 23 ºC | | Merck | 14,1404 | | BRN | 742031 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, peroxides, acids, acid chlorides, acid anhydrides, chloroformates. May be air sensitive. | | InChIKey | WDFQBORIUYODSI-UHFFFAOYSA-N | | CAS DataBase Reference | 106-40-1(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Bromoaniline(106-40-1) | | EPA Substance Registry System | p-Bromoaniline (106-40-1) |
| 4-Bromoaniline Usage And Synthesis |
| Chemical Properties | brown crystals | | Uses | 4-Bromoaniline is a brominated aniline used as a building block in the preparation or pharmaceutial and organic compounds. | | Uses | In preparation of azo dyes; condensed with formaldehyde in preparation of dihydroquinazolines. | | Uses | 4-Bromoaniline is used as a precursor in the production of azo dyes and dihydroquinazolines. It is also used as carbon and nitrogen supplement in the culture medium of Moraxella sp. strain G. Further, it is employed in the preparation of para-bromobiphenyl through Gomberg-Bachmann reaction. In addition to this, it is used as a building block in the preparation or pharmaceutical and organic compounds. | | Preparation | 4-bromoaniline can be made by reacting aniline with bromine with a protection with acetyl chloride. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 40, p. 1867, 1975 DOI: 10.1021/jo00900a053Synthetic Communications, 19, p. 3047, 1989 DOI: 10.1080/00397918908052699 | | General Description | Brown solid with a sweet odor. | | Air & Water Reactions | 4-Bromoaniline is sensitive to prolonged exposure to air. Vapor may form highly reactive mixtures in air . Insoluble in water. | | Reactivity Profile | Vapor may form highly reactive mixtures in air. | | Fire Hazard | Flash point data are not available for 4-Bromoaniline, but 4-Bromoaniline is probably combustible. | | Purification Methods | Crystallise the aniline (with appreciable loss) from aqueous EtOH. The benzoyl derivative has m 204o (from EtOH). [Beilstein 12 IV 1497.] |
| 4-Bromoaniline Preparation Products And Raw materials |
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