8-Anilino-1-naphthalenesulfonic acid Seven Chongqing Chemdad Co. ，Ltd

Product

8-Anilino-1-naphthalenesulfonic acid

CAS No.：82-76-8

Other grades of this product :

8-Anilino-1-naphthalenesulfonic acid Basic information

Product Name:	8-Anilino-1-naphthalenesulfonic acid
Synonyms:	1,8-ANS;1-ANILINONAPHTHALENE-8-SULFONIC ACID;8-ANILINO-1-NAPHTHALENESULFONIC ACID;ANS;ANSA;N-Phenyl-8-naphthylamine-1-sulfonic acid;N-PHENYL-1-NAPHTHYLAMINE-8-SULFONIC ACID;N-PHENYL PERI ACID
CAS:	82-76-8
MF:	C16H13NO3S
MW:	299.34
EINECS:	201-438-7
Product Categories:	Intermediates;Intermediates of Dyes and Pigments;Elisa Kit-plant ELISA Kit
Mol File:	82-76-8.mol

8-Anilino-1-naphthalenesulfonic acid Chemical Properties

Melting point	215-217 °C (dec.)(lit.)
density	1.409±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
solubility	DMF: soluble50mg/mL
form	Powder
pka	0.19±0.40(Predicted)
color	Dark green to brown to black
Merck	13,664
BRN	1843887
CAS DataBase Reference	82-76-8(CAS DataBase Reference)
EPA Substance Registry System	8-Anilino-1-naphthalenesulfonic acid (82-76-8)

Safety Information

Hazard Codes	Xi
Risk Statements	36-36/37/38
Safety Statements	26-36
WGK Germany	-
TSCA	Yes
HS Code	29214980

MSDS Information

Provider	Language
8-Anilino-1-naphthalenesulfonic acid	English
SigmaAldrich	English

8-Anilino-1-naphthalenesulfonic acid Usage And Synthesis

Description	1,8-ANS is a fluorescent dye that binds with high affinity to hydrophobic surfaces of proteins. 1,8-ANS has an excitation maximum of 350 nm. It has an emission maximum of 520 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FABP2) it has emission maxima of 468-477 nm. 1,8-ANS binds to low polarity regions of protein surfaces making it well suited for determining the affinity of hydrophobic ligands to their corresponding binding proteins, such as the binding of free fatty acids to FABPs. 1,8-ANS binds to FABP2 with a K_d value of approximately 9.7 μM at 24.5°C.
Chemical Properties	green needles
Uses	Intermediate of dyestuff
Uses	8-Anilino-1-naphthalenesulfonic Acid is used as a fluorescent probe to identify hydrophobic sites. Dyes and metabolites.

8-Anilino-1-naphthalenesulfonic acid Preparation Products And Raw materials

Raw materials

Aniline-->Peri acid

Preparation Products

ACID BLACK 24-->ACID BLUE 113-->IMMEDIAL BRILLIANT GREEN GB-->ACID BLUE 92-->disodium 5-((4-((4-chloro-3-sulfonatophenyl)azo)-1-naphthyl)azo)-8-(phenylamino)-1-naphthalenesulfonate-->IMMEDIAL BRILLIANT GREEN GB-->LUXOL FAST BLUE ARN-->ACID BLUE 113-->disodium 8-(phenylamino)-5-[[4-(phenylazo)-7-sulphonato-1-naphthyl]azo]naphthalenesulphonate-->5-Hydroxy-4-[[4-(phenylamino)-5-sulfo-1-naphthalenyl]azo]-1-naphthalenesulfonic acid disodium salt-->ACID BLACK 24-->Acid Blue 352:1-->Copper, 5-[(4-hydroxyphenyl)amino]-8-(phenylamino)-1-naphthalenesulfonic acid-sodium polysulfide condensate complexes, leuco derivs.-->Acid Blue 352

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