Sennoside A
Sennoside A
  • CAS No.:81-27-6
Other grades of this product :
Sennoside A Basic information
Product Name:Sennoside A
Synonyms:Sennoside A std.;SENNOSIDEA60%;SENNOSIDE A(P);SENNOSIDE A(SH);SENNOSIDA;CALCIUM SENNOSIDE 5%, 10%, 20%, 60%;[9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'R)-;Sennoside A1
CAS:81-27-6
MF:C42H38O20
MW:862.74
EINECS:201-339-9
Product Categories:The group of Sennosides;Anthraquinones, Hydroquinones and Quinones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File:81-27-6.mol
Sennoside A Chemical Properties
Melting point >191oC (dec.)
alpha D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane)
Boiling point 1144.8±65.0 °C(Predicted)
density 1.743±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
pka3.31±0.40(Predicted)
form neat
color Yellow to Dark Yellow
BRN 5723746
Stability:Hygroscopic
InChIKeyIPQVTOJGNYVQEO-KGFNBKMBSA-N
Safety Information
Risk Statements 22
Safety Statements 22-45
WGK Germany 3
3-10
HS Code 29173990
MSDS Information
ProviderLanguage
SigmaAldrich English
Sennoside A Usage And Synthesis
Chemical PropertiesLight yellow powder
Usesa natural anthroquinonone glucoside calcium complex with laxative properties
UsesSennoside A is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent.
Purification MethodsSennoside A (bianthraquinonyl-bis-glucoside R,R-enantiomer) [81-27-6] M 862.7, m 220 -2 4 0o(dec), [ ] D -164o (c 0.1, Me2CO/H2O 6:4), [ ] D -24o (c 0.2, 70% aqueous dioxane). Sennoside A forms yellow crystals from aqueous acetone, 2-ethoxyethanol or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3403.]
Sennoside A Preparation Products And Raw materials

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