| Sennoside A Basic information |
| Product Name: | Sennoside A |
| Synonyms: | Sennoside A std.;SENNOSIDEA60%;SENNOSIDE A(P);SENNOSIDE A(SH);SENNOSIDA;CALCIUM SENNOSIDE 5%, 10%, 20%, 60%;[9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'R)-;Sennoside A1 |
| CAS: | 81-27-6 |
| MF: | C42H38O20 |
| MW: | 862.74 |
| EINECS: | 201-339-9 |
| Product Categories: | The group of Sennosides;Anthraquinones, Hydroquinones and Quinones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
| Mol File: | 81-27-6.mol |
| Sennoside A Chemical Properties |
| Melting point | >191oC (dec.) |
| alpha | D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane) |
| Boiling point | 1144.8±65.0 °C(Predicted) |
| density | 1.743±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated) |
| pka | 3.31±0.40(Predicted) |
| form | neat |
| color | Yellow to Dark Yellow |
| BRN | 5723746 |
| Stability: | Hygroscopic |
| InChIKey | IPQVTOJGNYVQEO-KGFNBKMBSA-N |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Sennoside A Usage And Synthesis |
| Chemical Properties | Light yellow powder |
| Uses | a natural anthroquinonone glucoside calcium complex with laxative properties |
| Uses | Sennoside A is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent. |
| Purification Methods | Sennoside A (bianthraquinonyl-bis-glucoside R,R-enantiomer) [81-27-6] M 862.7, m 220 -2 4 0o(dec), [ ] D -164o (c 0.1, Me2CO/H2O 6:4), [ ] D -24o (c 0.2, 70% aqueous dioxane). Sennoside A forms yellow crystals from aqueous acetone, 2-ethoxyethanol or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3403.] |
| Sennoside A Preparation Products And Raw materials |
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