(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
  • CAS No.:14166-21-3
Other grades of this product :
(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Basic information
Product Name:(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE
Synonyms:(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE;TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE;TRANS-HEXAHYDROPHTHALIC ANHYDRIDE;1,3-Isobenzofurandione, hexahydro-, trans-;trans-cyclohexane-1,2-dicarboxylic anhydride;Einecs 238-009-9;cis-1.2-Cyclohexane dicarboxylic anhydride 1g [14166-21-3];trans-1,2-Cyclohexanedicarboxylic anhydride,trans-Hexahydrophthalic anhydride
CAS:14166-21-3
MF:C8H10O3
MW:154.16
EINECS:238-009-9
Product Categories:
Mol File:14166-21-3.mol
(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Chemical Properties
Melting point 145-147 °C(lit.)
Boiling point 283.4±0.0 °C(Predicted)
density 1.235±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Acetone (Sparingly), Chloroform (Slightly), DMSO (Slightly)
form Solid
color White to Pale Beige
Stability:Moisture Sensitive
CAS DataBase Reference14166-21-3
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-42/43-41
Safety Statements 26-27-36/37/39-37/39-24-23
WGK Germany 3
HS Code 29172090
MSDS Information
ProviderLanguage
SigmaAldrich English
(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Usage And Synthesis
UsesTrans-1,2-cyclohexanedicarboxylic anhydride can be used as a reagent to prepare hepatitis C virus (HCV) and granzyme B (indoline derivatives) inhibitors. It has also been employed in studies relating to the development of protein kinase C inhibitors.
Purification MethodsCrystallise the anhydride from *C6H6/Et2O. It has been obtained by heating the cis-acid or anhydride with HCl at 180o for 3hours. It can be obtained from the acid by heating in Ac2O. It sublimes at 125-135o/0.02mm. [Kohler & Jansen J Am Chem Soc 60 2145 1938, Fichter & Simon Helv Chim Acta 17 1218 1934, Beilstein 9 IV 2802.]
(+/-)-TRANS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE Preparation Products And Raw materials
Preparation ProductsCIS-1,2-CYCLOHEXANEDICARBOXYLIC ANHYDRIDE

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