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HUMAN IGF-II Basic information |
Product Name: | HUMAN IGF-II | Synonyms: | (2S)-1-acetyl-N-[(2S,3R)-1-[[(2S)-1-[[(2S)-3,3-dihydroxy-1-(4-hydroxyphenyl)butan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide;INSULIN-LIKE GROWTH FACTOR-II;INSULIN-LIKE GROWTH FACTOR-II HUMAN;INSULIN-LIKE GROWTH FACTOR-II, HUMAN, RECOMBINANT;IGF-II, HUMAN;IGF-2 HUMAN;IGF-II;HUMAN INSULIN-LIKE GROWTH FACTOR II | CAS: | 96081-16-2 | MF: | C24H36N4O9 | MW: | 0 | EINECS: | Product Categories: | Mol File: | Mol File |
HUMAN IGF-II Chemical Properties |
storage temp. | -20°C | form | lyophilized powder |
HUMAN IGF-II Usage And Synthesis |
Biochem/physiol Actions | Insulin-like growth factor II (IGF-II) also known as multiplication stimulating activity (MSA), shows virtually identical bioactivities as IGF-I. Expression of IGF-II is highest in fetal tissues, where it is believed to play a major role in overall growth and development. After birth IGF-II expression decreases to much lower levels in a variety of tissues. IGF-II is produced also in several tumors. IGF-II binds to IGF-II receptor (IGF-IIR), to IGF-IR and weakly to the insulin receptor (IR). All IGF-II bioactivities in adult tissues are generally attributed to its interaction with IGF-IR. However, during embryogenesis the roles of both IGF-IIR and IR may be significant in promoting normal growth. |
HUMAN IGF-II Preparation Products And Raw materials |
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