HEMOCYANIN, KEYHOLE LIMPET
HEMOCYANIN, KEYHOLE LIMPET
  • CAS No.:9013-72-3
Other grades of this product :
HEMOCYANIN, KEYHOLE LIMPET Basic information
Product Name:HEMOCYANIN, KEYHOLE LIMPET
Synonyms:MALEIMIDE ACTIVATED KEYHOLE LIMPET HEMOCYANIN;BLUE CARRIER(R);HAEMOCYANIN KEYHOLE LIMPET;HEMOCYANIN;HEMOCYANIN TYPE VIII;HEMOCYANIN-HG;HEMOCYANIN, KEYHOLE LIMPET;HEMOCYANIN, KEYHOLE LIMPET, MEGATHURA CRENULATA
CAS:9013-72-3
MF:
MW:0
EINECS:
Product Categories:Application Index;Serum Proteins;Serum Proteins and Related Enzymes
Mol File:Mol File
HEMOCYANIN, KEYHOLE LIMPET Chemical Properties
storage temp. 2-8°C
solubility H2O: soluble
form PBS solution
Safety Information
Risk Statements 52/53
Safety Statements 23-24/25-61
WGK Germany 1
10-21
MSDS Information
ProviderLanguage
SigmaAldrich English
HEMOCYANIN, KEYHOLE LIMPET Usage And Synthesis
UsesHemocyanin from Limulus polyphemus hemolymph has been used:
  • in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
  • as standard protein for pH based crystallization screening experiments
  • in peptide conjugation studies
UsesKeyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.
General DescriptionGastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.
Biochem/physiol ActionsThe largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).
HEMOCYANIN, KEYHOLE LIMPET Preparation Products And Raw materials

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