2-Chloro-1,3,2-dioxaphospholane

CAS No.：822-39-9

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

View the full Disclaimer

Other grades of this product :

2-Chloro-1,3,2-dioxaphospholane Basic information

Product Name:	2-Chloro-1,3,2-dioxaphospholane
Synonyms:	1,3,2-Dioxaphospholane, 2-chloro-;1,3,2-Dioxaphosphorane.2-chloro-;2-dioxaphospholane,2-chloro-3;Ethylenephosphorochloridite;AURORA KA-1222;ETHYLENE CYCL-CHLOROPHOSPHITE;ETHYLENE CYCLO-CHLOROPHOSPHITE;ETHYLENE CHLOROPHOSPHITE
CAS:	822-39-9
MF:	C2H4ClO2P
MW:	126.48
EINECS:	212-499-4
Product Categories:	Biochemistry;Nucleosides, Nucleotides & Related Reagents;Phosphorylating and Phosphorothioating Agents;Phosphorylation;Protecting Agents, Phosphorylating Agents & Condensing Agents;Synthetic Organic Chemistry;Phosphorylating and Phosphitylating Agents
Mol File:	822-39-9.mol

2-Chloro-1,3,2-dioxaphospholane Chemical Properties

Melting point	-28°C(lit.)
Boiling point	62 °C/20 mmHg (lit.)
density	1.422 g/mL at 25 °C (lit.)
refractive index	n20/D 1.489(lit.)
Fp	158 °F
storage temp.	2-8°C
form	clear liquid
color	Colorless to Light yellow
Sensitive	Moisture Sensitive
BRN	506179
CAS DataBase Reference	822-39-9(CAS DataBase Reference)
NIST Chemistry Reference	Ethylene chlorophosphite(822-39-9)
EPA Substance Registry System	1,3,2-Dioxaphospholane, 2-chloro- (822-39-9)

Safety Information

Hazard Codes	C
Risk Statements	14-34-37
Safety Statements	26-36/37/39-45-8-25
RIDADR	UN 3264 8/PG 2
WGK Germany	3
F	1-10
Hazard Note	Highly reactive cyclic phosphitylating reagent which
TSCA	Yes
HazardClass	8
PackingGroup	II

MSDS Information

Provider	Language
Ethylene glycol chlorophosphite	English
SigmaAldrich	English
ACROS	English
ALFA	English

2-Chloro-1,3,2-dioxaphospholane Usage And Synthesis

Chemical Properties	Clear Colourless Oil
Uses	Highly reactive cyclic phosphitylating reagent which provides fast coupling rates, and hydrolytic cleavage occurs more readily than with acyclic analogs
Uses	Ethylene chlorophosphite acts as a phosphitylating agent involved in the preparation of phosphocholine and spirophosphoranes. For example, it is used in the phosphorylation of p-tert-butyl(thia)calixarenes.

2-Chloro-1,3,2-dioxaphospholane Preparation Products And Raw materials

Preparation Products

2-Chloro-1,3,2-dioxaphospholane-2-oxide

Welcome！

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
+86-23-6139-8061 +86-13650506873
danny@chemdad.com sales@chemdad.com
www.chemdad.com
WhatsApp +86-13650506873