5-Methoxyindole-3-acetonitrile
5-Methoxyindole-3-acetonitrile
  • CAS No.:2436-17-1
Other grades of this product :
5-Methoxyindole-3-acetonitrile Basic information
Product Name:5-Methoxyindole-3-acetonitrile
Synonyms:5-METHOXY-3-INDOLYLACETONITRILE;5-METHOXYINDOLE-3-ACETONITRILE;(5-METHOXY-1H-INDOL-3-YL)ACETONITRILE;2-(5-Methoxy-1H-indol-3-yl)acetonitrile;5-METHOXY-3-INDOLYLACETONITRILE 97%;5-Methoxy indol - 3 -yl Acetonitrile;3-(Cyanomethyl)-5-methoxy-1H-indole;3-(Cyanomethyl)-5-methoxyindole
CAS:2436-17-1
MF:C11H10N2O
MW:186.21
EINECS:
Product Categories:Building Blocks;Heterocyclic Building Blocks;blocks;Carboxes;IndolesOxindoles;Indoles;Indoles and derivatives
Mol File:2436-17-1.mol
5-Methoxyindole-3-acetonitrile Chemical Properties
Melting point 65-69 °C (lit.)
Boiling point 175-177 °C(Press: 0.01 Torr)
density 1.224±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka16.02±0.30(Predicted)
color Very Dark Brown
CAS DataBase Reference2436-17-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
WGK Germany 3
HazardClass IRRITANT
HS Code 2933998090
MSDS Information
ProviderLanguage
SigmaAldrich English
5-Methoxyindole-3-acetonitrile Usage And Synthesis
Chemical PropertiesBrown powder
Uses5-Methoxyindole-3-acetonitrile is a versatile reactant used in the preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatment. It is also used in the synthesis of carboline analogs as potent MAPKAP-K2 inhibitors.
UsesReactant for preparation of (-)- and (+)-debromoflustramine B and its analogues as selective butyrylcholinesterase inhibitorsReactant for preparation of carboline analogs as potent MAPKAP-K2 inhibitorsReactant for preparation of indole-N-acetic acid derivatives as aldose reductase inhibitors for diabetic complications treatmentReactant for preparation of debromoflustramine B and labeled Me(3a)-13C-physostigmineReactant for preparation of physostigmine and physovenineReactant for preparation of phenethyl substituted indole derivatives as melatoninergic agonists and antagonists
5-Methoxyindole-3-acetonitrile Preparation Products And Raw materials

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