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| 4-(Trimethylsilyl)-3-butyn-2-one Basic information |
| 4-(Trimethylsilyl)-3-butyn-2-one Chemical Properties |
| Melting point | 99 °C | | Boiling point | 156 °C(lit.) | | density | 0.854 g/mL at 25 °C(lit.) | | refractive index | n20/D 1.442(lit.) | | Fp | 83 °F | | storage temp. | Flammables area | | form | clear liquid | | Specific Gravity | 0.854 | | color | Colorless to Light yellow to Light orange | | Hydrolytic Sensitivity | 4: no reaction with water under neutral conditions | | CAS DataBase Reference | 5930-98-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 10-36/37/38 | | Safety Statements | 16-26-36-37/39 | | RIDADR | UN 1224 3/PG 3 | | WGK Germany | 3 | | HazardClass | 3 | | PackingGroup | III | | HS Code | 29319090 |
| 4-(Trimethylsilyl)-3-butyn-2-one Usage And Synthesis |
| Chemical Properties | clear slightly yellow liquid | | Uses | 4-(Trimethylsilyl)-3-butyn-2-one (TMSB) has been used to investigate its asymmetric bioreduction to (S)-4-(trimethylsilyl)-3-butyn-2-ol {(S)-TMSBOL} by employing biocompatible water-immiscible ionic liquids (ILs). TMSB may be used for the synthesis of entecavir (BMS-200475). | | General Description | 4-(Trimethylsilyl)-3-butyn-2-one is a ketone. Its asymmetric bioreduction to enantiopure {(S)-TMSBOL in various hydrophilic ionic liquid (ILs) solvent systems has been reported. |
| 4-(Trimethylsilyl)-3-butyn-2-one Preparation Products And Raw materials |
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