1-BOC-1,10-DIAMINODECANE
1-BOC-1,10-DIAMINODECANE
  • CAS No.:216961-61-4
Other grades of this product :
1-BOC-1,10-DIAMINODECANE Basic information
Product Name:1-BOC-1,10-DIAMINODECANE
Synonyms:1,10-DIAMINODECANE, N1-BOC PROTECTED;1-BOC-1,10-DIAMINODECANE;TERT-BUTYL 10-AMINODECYLCARBAMATE;1,10-Diaminodecane, N1-BOC protected 97%;Boc-DADec;N-t-Butyloxycarbonyl-1,10-diaminodecane;Decane-1,10-diamine, N-BOC protected 97%;tert-Butyl (10-aminodec-1-yl)carbamate, 1,10-Diaminodecane, N-BOC protected
CAS:216961-61-4
MF:C15H32N2O2
MW:272.43
EINECS:
Product Categories:pharmacetical
Mol File:216961-61-4.mol
1-BOC-1,10-DIAMINODECANE Chemical Properties
Boiling point 380.4±15.0 °C(Predicted)
density 0.932±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka12.94±0.46(Predicted)
Safety Information
Hazard Codes Xi
Hazard Note Irritant
HS Code 2924190090
MSDS Information
1-BOC-1,10-DIAMINODECANE Usage And Synthesis
Descriptiontert-Butyl (10-aminodecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. tert-Butyl (10-aminodecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
1-BOC-1,10-DIAMINODECANE Preparation Products And Raw materials
Raw materials1,10-DIAMINODECANE-->Di-tert-butyl dicarbonate-->TRIMETHYLACETIC ANHYDRIDE-->tert-butyl azidoformate

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