| 1-(2,6-Dichlorophenyl)indolin-2-one Basic information |
| Product Name: | 1-(2,6-Dichlorophenyl)indolin-2-one |
| Synonyms: | Diclofenac PotassiumⅠ:1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one;Diclofenac Sodium ImpurityⅠ: 1-(2,6-Dichlorophenyl)-1,3-dihydro-2H-indol-2-one;Indolinone (Diclofenac Amide, Diclofenac Lactam);DICLOFENAC RELATED COMPOUND A (50 MG) (N-(2,6-DICHLOROPHENYL)INDOLIN-2-ONE);1-(2,6-Dichlorophenyl)-2,3-dihydro-1H-indole-2-one;Diclofenac Amide;6-Dichlorophenyl)-2-indolinone;N-(2,6-Dichlorophenyl)-Indolin-(2)-One |
| CAS: | 15362-40-0 |
| MF: | C14H9Cl2NO |
| MW: | 278.13 |
| EINECS: | 239-399-3 |
| Product Categories: | Aromatics, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;Aromatics;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 15362-40-0.mol |
| 1-(2,6-Dichlorophenyl)indolin-2-one Chemical Properties |
| Melting point | 115-119°C |
| Boiling point | 488.6±45.0 °C(Predicted) |
| density | 1.432±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | neat |
| pka | -4.85±0.20(Predicted) |
| color | Off-White to Light Brown |
| BRN | 1538309 |
| Stability: | Stability |
| CAS DataBase Reference | 15362-40-0(CAS DataBase Reference) |
| Safety Information |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| RTECS | NM3259200 |
| HS Code | 29337900 |
| MSDS Information |
| 1-(2,6-Dichlorophenyl)indolin-2-one Usage And Synthesis |
| Chemical Properties | Off-White to Light Brown Solid |
| Uses | 1-(2,6-Dichlorophenyl)indolin-2-one is a potential prodrug of Diclofenac and possible impurity during its commercial synthesis. It is Aceclofenac EP Impurity I and Diclofenac Impurity A. |
| 1-(2,6-Dichlorophenyl)indolin-2-one Preparation Products And Raw materials |
| Raw materials | DICLOFENAC METHYL ESTER-->2-(2,6-Dichloroanilino) benzaldehyde-->1-(2,6-Dichlorophenyl)indole-2,3-dione-->Diclofenac sodium-->Methanol |
| Preparation Products | Oxindole |
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