Other grades of this product :
| MYOSMINE Basic information |
| MYOSMINE Chemical Properties |
| Melting point | 42-44°C | | Boiling point | 82-83°C 0,5mm | | density | 1.12±0.1 g/cm3(Predicted) | | Fp | 82-83°C/0.5mm | | storage temp. | 2-8°C | | solubility | Methanol (Slightly), Water (Sparingly) | | form | Solid | | pka | pK1:5.26 (25°C) | | color | Light Beige to Dark Yellow | | BRN | 119254 | | Stability: | Moisture, Temperature Sensitive | | CAS DataBase Reference | 532-12-7(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | UT7660000 | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | HS Code | 29399990 |
| MYOSMINE Usage And Synthesis |
| Description | The alkaloids found in tobacco smoke may be separated into those which are
volatile in steam and those which are non-volatile. Myosmine occurs in the
former group and, although only present in small quantities, is the most fully
investigated of these bases. The alkaloid is normally obtained as an oily liquid
which may be crystallized. It is optically inactive and readily soluble in light
petroleum or Et20. It forms a hydrochloride as a microcrystalline powder which,
on sublimation yields colourless rods, m.p. ISS-8°C. The dihydrochloride, also a
microcrystalline powder, yields colourless needles on sublimation, m.p. 1S0-
17 Soc. The base also furnishes a dipicrate, m.p. 182-3°C (dec.) and a dipi_x0002_crolonate, m.p. 204°C (dec.). On dehydrogenation it gives 2-(3'-pyridyl)-pyrrole
(picrate, m.p. 200°C) identical with that obtained in a similar manner from nornicotine. According to Woodward and his colleagues, the alkaloid is one of
several products formed when nicotine is dehydrogenated over prepared quartz
at S70°C. It is readily hydrolyzed in H20 to yield 3-pyridyl-r-aminopropyl
ketone, forming a crystalline phenylhydrazone, m.p. 20l-2°C. | | Chemical Properties | Light Yellow Powder | | Uses | Myosmine is an alkaloid found in tobacco. Myosmine has been suspected to be a tobacco-independent carcinogenic source. | | Uses | mitogen | | Uses | Tobacco alkaloidReactant for:Nitrosation reactionsPeroxidation reaction with hydrogen peroxide | | Synthesis Reference(s) | Canadian Journal of Chemistry, 35, p. 651, 1957 DOI: 10.1139/v57-094The Journal of Organic Chemistry, 37, p. 1635, 1972Tetrahedron Letters, 8, p. 5185, 1967 | | References | Spath, Wenusch, Zajic., Ber., 69, 393 (1936)Woodward, Eisner, Haines., ibid, 69, 7S7 (1936)Spath, Wibaut, Kesztler., ibid, 71, 100 (1938) |
| MYOSMINE Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye