4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Basic information |
Product Name: | 4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE |
Synonyms: | 4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE;PyriMidine, 4,6-dichloro-5-nitro-2-(propylthio)-;4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine;4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine 4,6-dichloro-5-nitro-2-(propylsulfanyl)pyriMidine;4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDI;EOS-61674;4,6-Dichloro-5-nitro-2-(propythio)pyrimidine;4,6-Dichloro-5-nitro-2-propylthiopyridine |
CAS: | 145783-14-8 |
MF: | C7H7Cl2N3O2S |
MW: | 268.12 |
EINECS: | 700-475-0 |
Product Categories: | Intermediate of Ticagrelor;pyrimidine;Heterocycle-Pyrimidine series;145783-14-8 |
Mol File: | 145783-14-8.mol |
4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Chemical Properties |
Boiling point | 377.8±37.0 °C(Predicted) |
density | 1.54±0.1 g/cm3(Predicted) |
vapor pressure | 0.005Pa at 25℃ |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Sparingly), DMSO (Sparingly), Ethyl Acetate (Slightly) |
pka | -8.48±0.50(Predicted) |
form | Oil |
color | Colourless to Dark Yellow |
Stability: | Unstable in DMSO Solution |
LogP | 2.6 at 25℃ and pH7.3 |
Surface tension | 70.5-71.7mN/m at 9.1mg/L and 25℃ |
Safety Information |
HS Code | 2933599590 |
MSDS Information |
4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Usage And Synthesis |
Uses | 4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine is used as a reactnat in the synthesis of carba-nucleosides as potent antagonists of ADP purinergic receptor P2Y12 on human platelets. |
4,6-DICHLORO-5-NITRO-2-PROPYLTHIOPYRIMIDINE Preparation Products And Raw materials |
Raw materials | 6-HYDROXY-2-(PROPYLTHIO)-4(3H)-PYRIMIDINONE-->5-nitro-2-(propylthio)pyriMdine-4,6-diol-->N,N-Diethylaniline-->N,N-Dimethylaniline |
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