| 4-(METHOXYCARBONYL)PHENYLBORONIC ACID Basic information |
| Product Name: | 4-(METHOXYCARBONYL)PHENYLBORONIC ACID |
| Synonyms: | RARECHEM AH PB 0115;P-(METHOXYCARBONYL)PHENYLBORONIC ACID;METHYL 4-BORONOBENZOATE;AKOS BRN-0122;4-METHOXYCARBONYLBENZENEBORONIC ACID;4-METHOXYCARBONYLPHENYLBORONIC ACID;4-CARBOMETHOXYPHENYLBORONIC ACID;Methyl 4-boronobenzoate 4-(Methoxycarbonyl)phenylboronic acid |
| CAS: | 99768-12-4 |
| MF: | C8H9BO4 |
| MW: | 179.97 |
| EINECS: | 619-459-9 |
| Product Categories: | Aryl;Boronic acid;blocks;Acids and Derivatives;Boron, Nitrile, Thio,& TM-Cpds;Organoborons;BoronicAcids;Carboxes;Boronic Acid series;Boronic acids;B (Classes of Boron Compounds);CHIRAL CHEMICALS;Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Monosubstituted Aryl Boronic Acids;Organometallic Reagents;Boronate Ester;Potassium Trifluoroborate |
| Mol File: | 99768-12-4.mol |
| 4-(METHOXYCARBONYL)PHENYLBORONIC ACID Chemical Properties |
| Melting point | 197-200 °C (lit.) |
| Boiling point | 345.8±44.0 °C(Predicted) |
| density | 1.25±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in methanol. |
| form | powder |
| pka | 7.69±0.10(Predicted) |
| color | white to off-white |
| CAS DataBase Reference | 99768-12-4(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 37/39-26 |
| WGK Germany | 3 |
| TSCA | No |
| HazardClass | IRRITANT |
| HS Code | 29163990 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ACROS | English |
| 4-(METHOXYCARBONYL)PHENYLBORONIC ACID Usage And Synthesis |
| Chemical Properties | White to light yellow crystal powde |
| Uses | 4-(Methoxycarbonyl)phenylboronic Acid is a reagent used for• ;Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence1 • ;Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides2 • ;One-pot ipso-nitration of arylboronic acids3 • ;Copper-catalyzed nitration4 • ;Cyclocondensation followed by palladium-phosphine-catalyzed Suzuki-Miyaura coupling5 • ;Reagent used in Preparation of• ;Biaryls via nickel-catalyzed Suzuki-Miyaura cross-coupling reaction of aryl halides with arylboronic acid6† • ;Chromenones and their |
| Uses | suzuki reaction |
| Uses | 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor. |
| 4-(METHOXYCARBONYL)PHENYLBORONIC ACID Preparation Products And Raw materials |
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