4-N-BOC-Aminopiperidine Ten Chongqing Chemdad Co. ，Ltd

Product

4-N-BOC-Aminopiperidine

CAS No.：73874-95-0

Other grades of this product :

4-N-BOC-Aminopiperidine Basic information

Product Name:	4-N-BOC-Aminopiperidine
Synonyms:	4-(TERT-BUTOXYCARBONYLAMINO)PIPERIDINE;4-N-TERT-BOC-AMINO PIPERIDINE;4-N-(TERT-BUTOXYCARBONYL)AMINOPIPERIDINE;4-BOC-AMINOPIPERIDINE;4-AMINOPIPERIDINE, 4-BOC PROTECTED;4-(N-BOC-AMINO)PIPERIDINE;4-(tert-ButoxycarbonylaMino)piperidine, 98.0%(GC&T;CARBAMIC ACID, 4-PIPERIDINYL-, 1,1-DIMETHYLETHYL ESTER
CAS:	73874-95-0
MF:	C10H20N2O2
MW:	200.28
EINECS:	616-026-6
Product Categories:	Pyrans, Piperidines & Piperazines;Building Blocks;Pyridine series;Pyrans, Piperidines &Piperazines;Piperidines;Heterocyclic Building Blocks;Amines;blocks;pharmacetical;Piperidine
Mol File:	73874-95-0.mol

4-N-BOC-Aminopiperidine Chemical Properties

Melting point	162-166 °C(lit.)
Boiling point	80°C/0.05mm
density	1.02±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	12.39±0.20(Predicted)
form	Crystalline Powder
color	Off-white
Sensitive	Air Sensitive
InChIKey	CKXZPVPIDOJLLM-UHFFFAOYSA-N
CAS DataBase Reference	73874-95-0(CAS DataBase Reference)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36-37/39
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339900

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

4-N-BOC-Aminopiperidine Usage And Synthesis

Description	4-(N-Boc-amino)piperidone may be used as a functionalization reagent for introduction of a primary and a tertiary amino group to poly(2-isopropyl-2-oxazoline. It can also be used as pharma building block. It is used in the synthesis of a piperidine-4-carboxamide CCR5 antagonist with potent anti-HIV 1-activity. It is an intermediate for the synthesis of various pharmaceutical and biologically active compounds, including inhibitors and therapeutic agents. It is used for the synthesis of diphenyl purine derivatives as peripherally selective cannabinoid receptor 1 Antagonists.
Chemical Properties	off-white crystalline powder
Uses	Pharma building block.
General Description	4-(N-Boc-amino)piperidone is a piperidone derivative.

4-N-BOC-Aminopiperidine Preparation Products And Raw materials

Raw materials

Hydrochloric acid-->Ethyl acetate-->Methanol-->Acetic acid-->Potassium carbonate-->Chloroform-->Government regulation-->Sodium nitrite-->Acetone-->Palladium-->Hydrazinium hydroxide solution-->Di-tert-butyl dicarbonate-->Benzyl bromide-->2,3-DICHLORO-5,8-DIHYDROXY-1,4-NAPHTHOQUINONE-->1,1'-Carbonyldiimidazole-->Isonipecotic acid-->Methyl isonipecotate-->BENZYL 4-ISOCYANATOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE-->4-Amino-1-benzylpiperidine

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