Other grades of this product :
| TCO-PEG4-Acid Basic information |
| Product Name: | TCO-PEG4-Acid | | Synonyms: | (4E)-TCO-PEG4-acid;TCO-PEG4-Acid;TCO4-PEG4-COOH;5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid, 1-(4-cycloocten-1-yl) ester | | CAS: | 1802913-21-8 | | MF: | C20H35NO8 | | MW: | 417.49 | | EINECS: | | Product Categories: | SiChem | | Mol File: | 1802913-21-8.mol |
| TCO-PEG4-Acid Chemical Properties |
| solubility | Soluble in DMSO, DCM, DMF |
| TCO-PEG4-Acid Usage And Synthesis |
| Description | TCO-PEG4-acid is a click chemistry linker containing a TCO (trans-cycloctene) and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators such as EDC. , TCO reagent is highly reactive with tetrazine in an inverse electron demand Diels Alder (IEDDA) reaction followed by a retro-DA reaction. The hydrophilic PEG spacer increases solubility in aqueous media. |
| TCO-PEG4-Acid Preparation Products And Raw materials |
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