BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
  • CAS No.:756525-91-4
Other grades of this product :
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Basic information
Product Name:BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID
Synonyms:BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID;Boc-NH-PEG4-CH2CH2COOH;15-(Boc-aMino)-4,7,10,13-tetraoxapentadecanoic acid;3-[2-[2-[2-[2-(tert-Butoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid;5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(1,1-dimethylethyl) ester;N-(tert-Butyloxycarbonyl)-15-amino-4,7,10,13-tetraoxapentanedecanoic acid;2,2-DiMethyl-4-oxo-3,8,11,14,17-pentaoxa-5-azaicosan-20-oic acid;t-Boc-N-amido-PEG4-acid
CAS:756525-91-4
MF:C16H31NO8
MW:365.42
EINECS:
Product Categories:ADCs Linkers;PEG
Mol File:756525-91-4.mol
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Chemical Properties
Boiling point 504.5±50.0 °C(Predicted)
density 1.124±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 2-8°C
pka4.28±0.10(Predicted)
λmax254nm(lit.)
InChIKeyYCEYBRZRNOJORY-UHFFFAOYSA-N
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29225090
MSDS Information
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Usage And Synthesis
Descriptiont-Boc-N-amido-PEG4-acid is a PEG linker containing a terminal carboxylic acid and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
Chemical PropertiesYellow oil
Uses15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid is used as a substitution variant of cocaine esterase with improved stability and its use in treatment of cocaine overdose.
BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID Preparation Products And Raw materials
Preparation ProductsMaleimide-PEG4-NHS Ester

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