Other grades of this product :
| Boc-Hyp-OH Basic information |
| Product Name: | Boc-Hyp-OH | | Synonyms: | (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;(2S,4R)-N-t-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid;Boc-(2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic Acid;N-ter;N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline ,98%;Boc-L-trans-hydroxyproline(Boc-trans-Hyp-OH) ,98.5%(HPLC);1,2-Pyrrolidinedicarboxylicacid,4-hydroxy-,1-(1,1-diMethylethyl)ester,(2S,4R)-;(2S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid | | CAS: | 13726-69-7 | | MF: | C10H17NO5 | | MW: | 231.25 | | EINECS: | 604-011-7 | | Product Categories: | Hydroxyproline [Hyp];Unusual Amino Acids;AMINOACIDS DERIVATIVES;Pyrrole&Pyrrolidine&Pyrroline;Amino Acids;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino acid series;1;bc0001 | | Mol File: | 13726-69-7.mol |
| Boc-Hyp-OH Chemical Properties |
| Melting point | 123-127 °C(lit.) | | alpha | -78 º (in H2O) | | Boiling point | 390.9±42.0 °C(Predicted) | | density | 1.312±0.06 g/cm3(Predicted) | | refractive index | -68 ° (C=1, MeOH) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | pka | 3.80±0.40(Predicted) | | form | Powder | | color | White to off-white | | optical activity | [α]20/D 53.5±2°, c = 1% in DMF | | Water Solubility | very faint turbidity | | BRN | 4295484 | | InChIKey | BENKAPCDIOILGV-RQJHMYQMSA-N | | CAS DataBase Reference | 13726-69-7(CAS DataBase Reference) | | EPA Substance Registry System | (2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | HS Code | 2933 99 80 | | HazardClass | IRRITANT |
| Boc-Hyp-OH Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive. | | Biological Activity | Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. |
| Boc-Hyp-OH Preparation Products And Raw materials |
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