Other grades of this product :
| propargyl-PEG3-Acid Basic information |
| Product Name: | propargyl-PEG3-Acid | | Synonyms: | propargyl-PEG3-Acid;Propargyl-PEG4-(CH2)3-acid;Propyne-PEG2-CH2CH2COOH;Alkyne-PEG3-COOH;3-{2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy}propanoic acid;PROPARGYL-PEG3-COOH;3-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoic acid;Propargyl-PEG2-CH2CH2COOH | | CAS: | 1347760-82-0 | | MF: | C10H16O5 | | MW: | 216.23 | | EINECS: | | Product Categories: | peg | | Mol File: | 1347760-82-0.mol |
| propargyl-PEG3-Acid Chemical Properties |
| storage temp. | -20°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | clear liquid | | color | Light yellow to Brown |
| propargyl-PEG3-Acid Usage And Synthesis |
| Description | Propargyl-PEG3-acid is a reagent with an alkyne group and a carboxylic acid. The terminal carboxylic acid can form amide bond with primary amines (activation is needed). The alkyne can form triazole linkage with azide containing molecules via copper catalyzed reactions. | | Uses | Propargyl-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a carboxylic acid at one end and propargyl group at the other for reaction with azide-containing compounds using click chemistry. The hydrophillic PEG linker facilitates solubility in biological applications. Propargyl-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation. |
| propargyl-PEG3-Acid Preparation Products And Raw materials |
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