DBCO-amine
DBCO-amine
  • CAS No.:1255942-06-3
Other grades of this product :
DBCO-amine Basic information
Product Name:DBCO-amine
Synonyms:Dibenzocyclooctyne-aMine for Copper-free Click CheMistry;ADIBO-CH2CH2NH2·TFA;Azadibenzocyclooctyne-(CH2)2-amine TFA;DBCO-amine;DBCO-NH2;Dibenzocyclooctyne-amine;DBCO-(CH2)2-NH2.TFA;DBCO-(CH2)3-NH2.TFA
CAS:1255942-06-3
MF:C18H16N2O
MW:276.33
EINECS:
Product Categories:DBCO
Mol File:1255942-06-3.mol
DBCO-amine Chemical Properties
Melting point 86-96°C
Boiling point 549.9±50.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
storage temp. -20°C
pka8.81±0.10(Predicted)
form Solid
color Yellow to Orange
InChIKeyPQFQVUMDOWUGMK-CHMOPDDRSA-N
Safety Information
WGK Germany 3
HS Code 29339900
MSDS Information
DBCO-amine Usage And Synthesis
DescriptionDBCO-amine is a simple building block containing a DBCO moiety and will add minimal spacer to the modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions.
UsesAzadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
UsesDBCO-Amine was useful for the study of labelled T-cells, which were used to predict the therapeutic efficacy of adoptive T-cell therapy.
DBCO-amine Preparation Products And Raw materials

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