N-Vinyl-2-pyrrolidone
N-Vinyl-2-pyrrolidone
  • CAS No.:88-12-0
Other grades of this product :
N-Vinyl-2-pyrrolidone Basic information
Description
Product Name:N-Vinyl-2-pyrrolidone
Synonyms:1-VINYL-2-PYRROLIDINONE, 99+%;N-Vinyl-2-pyrrolidone, stabilized with Kerobit;N-Vinyl-2-pyrrolidone, stabilized, 98%;N-VINYL-2-PYRROLIDINONE;N-VINYL-2-PYRROLIDONE;N-VINYLPYRROLIDONE;N-VINYLBUTYROLACTAM;1-ethenyl-2-pyrrolidinon
CAS:88-12-0
MF:C6H9NO
MW:111.14
EINECS:201-800-4
Product Categories:monomer;88-12-0
Mol File:88-12-0.mol
N-Vinyl-2-pyrrolidone Chemical Properties
Melting point 13-14 °C
Boiling point 92-95 °C11 mm Hg(lit.)
density 1.04 g/mL at 25 °C(lit.)
vapor density 3.8 (vs air)
vapor pressure 0.1 mm Hg ( 24 °C)
refractive index n20/D 1.512(lit.)
Fp 201 °F
storage temp. Store below +30°C.
solubility 52.1g/l soluble
form Liquid
pka-0.34±0.20(Predicted)
color Clear colorless to yellow
PH9-10 (100g/l, H2O, 20℃)
explosive limit1.4-10%(V)
Water Solubility miscible
Merck 14,7697
BRN 110513
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyWHNWPMSKXPGLAX-UHFFFAOYSA-N
LogP0.4 at 25℃
CAS DataBase Reference88-12-0(CAS DataBase Reference)
NIST Chemistry ReferenceN-Vinylpyrrolidone(88-12-0)
IARC3 (Vol. 19, Sup 7, 71) 1999
EPA Substance Registry SystemN-Vinyl-2-pyrrolidone (88-12-0)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-37-40-41-48/20
Safety Statements 26-36/37/39
RIDADR UN 2810 6.1/PG 3
WGK Germany 1
RTECS UY6107000
Autoignition Temperature685 °F
HazardClass 6.1
PackingGroup III
HS Code 29337900
Hazardous Substances Data88-12-0(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 1022 mg/kg
MSDS Information
ProviderLanguage
1-Vinyl-2-pyrrolidone English
ACROS English
SigmaAldrich English
ALFA English
N-Vinyl-2-pyrrolidone Usage And Synthesis
DescriptionN-vinyl-2-pyrrolidone (NVP) is commonly used as a reactive diluent for radiation curing in UV-coating, UV-inks, and UV adhesives. It is used as a monomer to produce water soluble polyvinylpyrrolidone (PVP) with uses in pharmaceuticals, oil field, cosmetics, food additives & adhesives. It is used in the manufacture of copolymers with, for example, acrylic acid, acrylates, vinyl acetate and acrylonitrile and in the synthesis of phenolic resins.
Chemical PropertiesColorless liquid. Combustible.
Uses1-Vinyl-2-pyrrolidinone is used in the preparation of NMDA receptor antagonists. Also used in the synthesis of copolymers used to stabilize rhodium nanoclusters.
UsesA pyrrolidine used for biochemical research
General Description1-Vinyl-2-pyrrolidinone is a colorless to yellow liquid, with a characteristic odor. Its melting point is around 13.5oC and boils at about 90-92oC. VP is completely miscible in water and in most organic solvents but partially miscible in aliphatic hydrocarbons. Industrial production of VP by reacting 2-pyrrolidone with acetylene at high pressure and temperature has been reported. The vinylation process proceeds in liquid phase and is catalyzed by 3-pyrrolidone -potassium hydroxide.
Safety ProfileConfirmed carcinogen. Moderately toxic by ingestion, inhalation, and skin contact. A severe eye irritant. Probably irritating and narcotic in high concentrations. Combustible when exposed to heat or flame; can react vigorously with oxibzing materials. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx.
N-Vinyl-2-pyrrolidone Preparation Products And Raw materials
Raw materialsPotassium hydroxide-->Nickel-->Ethylene glycol-->Cyclohexane-->Succinimide
Preparation Products5-Methylindole-->Polyvinylpyrrolidone-->METHYL 2-(2-BROMOPHENYL)ACETATE-->(+/-)-NICOTINE-->6-Methoxyindole

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