Mal-PEG8-COOH
Mal-PEG8-COOH
  • CAS No.:1334177-86-4
Other grades of this product :
Mal-PEG8-COOH Basic information
Product Name:Mal-PEG8-COOH
Synonyms:Mal-PEG8-COOH;1-Maleimido-3-oxo-7,10,13,16,19,22,25,28-octaoxa-4-aza-hentriacontan-31-oic acid;MALEIMIDE-NH-PEG8-CH2CH2COOH;Mal-amido-PEG8-acid;Maleimide-PEG8-propionic acid;31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid;MAL-AMIDO-PEG8-COOH;Mal-NH-PEG8-COOH
CAS:1334177-86-4
MF:C26H44N2O13
MW:592.63
EINECS:
Product Categories:Monodispersed PEG Derivatives;PEGylation Reagents;peg
Mol File:1334177-86-4.mol
Mal-PEG8-COOH Chemical Properties
Boiling point 747.9±60.0 °C(Predicted)
density 1?+-.0.06 g/cm3(Predicted)
pka4.28±0.10(Predicted)
Safety Information
MSDS Information
Mal-PEG8-COOH Usage And Synthesis
DescriptionMal-amido-PEG8-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses31-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-4,7,10,13,16,19,22,25-octaoxa-28-azahentriacontanoic Acid is reactant in the light-induced endosomal lysis events in fibroblast, normal, and carcinoma cell lines using a colloidal mesoporous silica (CMS) nanoparticle.
Mal-PEG8-COOH Preparation Products And Raw materials

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