2-Naphthalenesulfonyl chloride
2-Naphthalenesulfonyl chloride
  • CAS No.:93-11-8
Other grades of this product :
2-Naphthalenesulfonyl chloride Basic information
Product Name:2-Naphthalenesulfonyl chloride
Synonyms:NAPHTHALENE-BETA-SULFONYL CHLORIDE;NAPHTHALENE-2-SULFONYL CHLORIDE;NAPHTHALENE-2-SULPHONYL CHLORIDE;2-NAPHTHALENESULFONYL CHLORIDE;AKOS B022434;ART-CHEM-BB B022434;BETA-NAPHTHALENE SULFONYL CHLORIDE;2-Naphthalenylsulfonyl chloride
CAS:93-11-8
MF:C10H7ClO2S
MW:226.68
EINECS:202-219-9
Product Categories:Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Building Blocks;Chemical Synthesis;Indolines ,Indoles ,Indazoles;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Indazoles
Mol File:93-11-8.mol
2-Naphthalenesulfonyl chloride Chemical Properties
Melting point 74-76 °C (lit.)
Boiling point 147.7 °C/0.6 mmHg (lit.)
density 1.3661 (estimate)
vapor pressure 0.004Pa at 25℃
Fp 200-202°C/13mm
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Toluene
form Powder
color Light yellow to beige
Water Solubility insoluble
Sensitive Moisture Sensitive
BRN 641898
InChIKeyOPECTNGATDYLSS-UHFFFAOYSA-N
LogP2.2 at 25℃
CAS DataBase Reference93-11-8(CAS DataBase Reference)
NIST Chemistry Reference2-Naphthalenesulfonyl chloride(93-11-8)
EPA Substance Registry System2-Naphthalenesulfonyl chloride (93-11-8)
Safety Information
Hazard Codes C
Risk Statements 34
Safety Statements 26-36/37/39-45-27
RIDADR UN 3261 8/PG 2
WGK Germany 3
21
TSCA Yes
HazardClass 8
PackingGroup II
HS Code 29049020
MSDS Information
ProviderLanguage
2-Naphthalenesulfonyl chloride English
SigmaAldrich English
ACROS English
ALFA English
2-Naphthalenesulfonyl chloride Usage And Synthesis
Chemical PropertiesLIGHT YELLOW TO BEIGE POWDER
Uses2-Naphthalenesulfonyl chloride was employed as capping reagent for primary amine to convert histamine to a selective histamine H3-receptor antagonist. It was used for pre-column derivatization during the high-performance liquid chromatographic assay of neomycin sulfate.
Flammability and ExplosibilityNotclassified
Purification MethodsDistil the chloride in a vacuum and/or recrystallise it (twice) from *benzene/pet ether (1:1 v/v). Purify it as the 1-sulfonyl chloride above. [Fierz-Davaid & Weissenbach Helv Chim Acta 3 2312 1920.] The sulfonamide has m 217o (from EtOH). [Beilstein 11 III 399, 11 IV 529.]
2-Naphthalenesulfonyl chloride Preparation Products And Raw materials
Preparation ProductsNAPHTHALENE-2-SULFONAMIDE

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