5-Nitrothiophene-2-carboxylic acid
5-Nitrothiophene-2-carboxylic acid
  • CAS No.:6317-37-9
Other grades of this product :
5-Nitrothiophene-2-carboxylic acid Basic information
Product Name:5-Nitrothiophene-2-carboxylic acid
Synonyms:RARECHEM AL BO 0544;5-Nitro-2-thenoic acid;5-NITRO-2-THIOPHENECARBOXYLIC ACID;5-NITROTHIOPHENE-2-CARBOXYLIC ACID;BUTTPARK 121\04-13;5-Nitro-2-ThiphenecarboxylicAcid;5-nitro-2-thiophenecarboxylic;2-Carboxy-5-nitrothiophene
CAS:6317-37-9
MF:C5H3NO4S
MW:173.15
EINECS:228-654-4
Product Categories:Carboxylic Acids;Thiophenes & Benzothiophenes;Carboxylic Acids;Building Blocks;Heterocyclic Building Blocks;Thiophenes;Heterocycles;Thiophenes & Benzothiophenes;Thiophene&Benzothiophene
Mol File:6317-37-9.mol
5-Nitrothiophene-2-carboxylic acid Chemical Properties
Melting point 154-159℃
Boiling point 367.2±27.0 °C(Predicted)
density 1.676±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka2.69±0.10(Predicted)
form Solid
color Pale yellow
InChIKeyUNEPVPOHGXLUIR-UHFFFAOYSA-N
CAS DataBase Reference6317-37-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 24/25
WGK Germany 3
Hazard Note Irritant
HS Code 29349990
MSDS Information
ProviderLanguage
SigmaAldrich English
5-Nitrothiophene-2-carboxylic acid Usage And Synthesis
Chemical PropertiesSolid
Uses5-Nitrothiophene-2-carboxylic Acid is a reagent used in the preparation of benzothiophene amides which fuctions as nicotinamide ribosyltransferase inhibitors with potential antitumor and anticancer activities. It also functions as an intermediate in varying organic transformations.
Synthesis Reference(s)Canadian Journal of Chemistry, 44, p. 2881, 1966 DOI: 10.1139/v66-428Journal of Medicinal Chemistry, 34, p. 2112, 1991
5-Nitrothiophene-2-carboxylic acid Preparation Products And Raw materials
Raw materialsAcetic acid-->Nitric acid-->Acetic anhydride-->2-Thiophenecarboxylic acid
Preparation Products5-Amino-thiophene-2-carboxylic acid methyl ester

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