6-Chloropurine
6-Chloropurine
  • CAS No.:87-42-3
Other grades of this product :
6-Chloropurine Chemical Properties
Melting point >300 °C (dec.) (lit.)
Boiling point 254.17°C (rough estimate)
density 1.4649 (rough estimate)
refractive index 1.8430 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility 5 g/L
form crystalline
pka7.47±0.20(Predicted)
color yellow-orange
Water Solubility 5 g/L
Merck 14,2161
BRN 5774
InChIKeyZKBQDFAWXLTYKS-UHFFFAOYSA-N
CAS DataBase Reference87-42-3(CAS DataBase Reference)
NIST Chemistry Reference6-Chloropurine(87-42-3)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38-20/21/22
Safety Statements 26-36-36/37/39
WGK Germany 3
RTECS UO7520000
10-23
HazardClass IRRITANT
HS Code 29335990
ToxicityLD50 oral in mouse: 720mg/kg
MSDS Information
ProviderLanguage
6-Chloropurine English
ACROS English
SigmaAldrich English
ALFA English
6-Chloropurine Usage And Synthesis
Chemical PropertiesWhite crystals
Uses6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide. It is also used to prepare 6-succinoaminopurine.
Uses6-Chloropurine has been used in the preparation of:
  • 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO
  • 6-succinoaminopurine
Synthesis Reference(s)Journal of the American Chemical Society, 78, p. 1928, 1956 DOI: 10.1021/ja01590a043
General DescriptionThe acid-catalyzed reaction of 6-chloropurine with 3,4-di-O-acetyl-D-xylal has been investigated.
Purification Methods6-Chloropurine crystallises from water. The UV in water at pH 1 has 264nm (log 3.94). [Beilstein 26 III/IV 1742.]

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