5,6-Dimethoxyindole
5,6-Dimethoxyindole
  • CAS No.:14430-23-0
Other grades of this product :
5,6-Dimethoxyindole Basic information
Product Name:5,6-Dimethoxyindole
Synonyms:5,6-Dimethoxyindole,99%;5,6-Dimethoxy-1H-indole 99%;5,6-Dimethoxy-1H-indole99%;AKOS JY2083477;5,6-DIMETHOXYINDOLE;5,6-DIMETHOXY-1H-INDOLE;1H-Indole, 5,6-dimethoxy-;5,6-Dimethoxyindole 99%
CAS:14430-23-0
MF:C10H11NO2
MW:177.2
EINECS:238-402-5
Product Categories:Amines;Aromatics;Heterocyclic Compounds;Indole Derivatives;Building Blocks;Heterocyclic Building Blocks;Indoles and derivatives;Indoline & Oxindole;Indoles
Mol File:14430-23-0.mol
5,6-Dimethoxyindole Chemical Properties
Melting point 154-157 °C (lit.)
Boiling point 198°C 8mm
density 1.182±0.06 g/cm3(Predicted)
Fp 198°C/8mm
storage temp. Sealed in dry,Room Temperature
pka16.93±0.30(Predicted)
form Powder
color Beige
Water Solubility Insoluble in water.
λmax306nm(EtOH)(lit.)
BRN 5683
InChIKeyQODBZRNBPUPLEZ-UHFFFAOYSA-N
CAS DataBase Reference14430-23-0(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Safety Statements 22-24/25
WGK Germany 3
10
HazardClass IRRITANT
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5,6-Dimethoxyindole Usage And Synthesis
Chemical PropertiesBeige powder
Uses5,6-Dimethoxyindole is an indole derivative as analgesic antiinflammatory. It was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.
Application5,6-Dimethoxyindole was used in the synthesis of N-benzyl-N-cyclopropyl-5,6-dimethoxyindole-3-glyoxalamide.Reactant in synthesis of indolylhydroxyoxindoles via enantioselective Friedel-Crafts reactionReactant in synthesis of benzyl trimethoxyindolesReactant for synthesis of benzoylpiperazinyl-indolyl ethane dione derivatives as HIV-1 inhibitorsReactant for synthesis of 1-aroylindole 3-aroylindoles combretastatin A-4 analogs as antitumor agents and tubulin polymerization inhibitorsReactant for preparation of tryptophanol derivatives via the Grignard reaction
Synthesis Reference(s)Journal of the American Chemical Society, 75, p. 5887, 1953 DOI: 10.1021/ja01119a030Synthesis of 5,6-Dimethoxyindoles and 5,6-Dimethoxyoxindoles. A New Synthesis of Indoles DOI: 10.1021/ja01619a049
5,6-Dimethoxyindole Preparation Products And Raw materials

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