3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
  • CAS No.:72578-71-3
Other grades of this product :
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Basic information
Product Name:3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
Synonyms:3-(2-chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2h-1,3,2-oxazaphosphorine-2-oxide;IfofaMide acylation objects;(R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone;IFOSFAMIDEACYLATE;3-(2-CHLOROACETYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE;3-(2-CHLOROACTYL)-2-[(2-CHLOROETHYL)AMINO]TETRAHYDRO-2H-1,3,2-OXAZAPHOSPHORINE-2-OXIDE ,98%;Ifosfamide acylation objects;IfosfamideIntermediate
CAS:72578-71-3
MF:C7H13Cl2N2O3P
MW:275.07
EINECS:1806241-263-5
Product Categories:
Mol File:72578-71-3.mol
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Chemical Properties
Boiling point 355.0±52.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
storage temp. 2-8°C
pka-1.29±0.20(Predicted)
Safety Information
MSDS Information
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Usage And Synthesis
Chemical PropertiesWhite crystalline powder
Uses(R)-2-Chloro-1-(2-((2-chloroethyl)amino)-2-oxido-1,3,2-oxazaphosphinan-3-yl)ethanone is an intermediate in the preparation of Ifosfamide (I265000), a cytostatic agent, related structurally to cyclophosphamide.
Usesantineoplastic agent and antimetabolite
3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide Preparation Products And Raw materials
Raw materialsdechloroethylcyclophosphamide-->Chloroacetyl chloride

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