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| 19-HYDROXY-4-ANDROSTENE-3,17-DIONE Basic information |
| Product Name: | 19-HYDROXY-4-ANDROSTENE-3,17-DIONE | | Synonyms: | 19-HYDROXY-4-ANDROSTEN-3,17-DIONE;19-HYDROXY-4-ANDROSTENE-3,17-DIONE;19-HYDROXYANDROSTENDIONE;19-HYDROXYANDROSTENEDIONE;Androst-4-ene-3,17-dione, 19-hydroxy-;19-hydroxyandrost-4-ene-3,17-dione;4-ANDROSTENE-3,17-DIONE-19-0L;4-ANDROSTENE-3,17-DIONE-19-OL | | CAS: | 510-64-5 | | MF: | C19H26O3 | | MW: | 302.41 | | EINECS: | 208-116-5 | | Product Categories: | All Inhibitors;Inhibitors;Steroids | | Mol File: | 510-64-5.mol |
| 19-HYDROXY-4-ANDROSTENE-3,17-DIONE Chemical Properties |
| Melting point | 168-169 °C(lit.) | | Boiling point | 485.4±45.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Store in freezer, under -20°C | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.90±0.10(Predicted) | | color | Off-White to Pale Yellow | | optical activity | [α]/D +190±5°, c = 1 in chloroform | | BRN | 2567249 | | CAS DataBase Reference | 510-64-5(CAS DataBase Reference) | | NIST Chemistry Reference | 19-Hydroxyandrost-4-ene-3,17-dione(510-64-5) |
| 19-HYDROXY-4-ANDROSTENE-3,17-DIONE Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | A novel substituted estrogen as aromatase inhibitor | | Uses | 19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor. | | Purification Methods | Recrystallise 19-hydroxy-4-androsten-3,17-dione from Me2CO/hexane or Et2O/hexane. It has UV with max at 242nm in EtOH or MeOH. The 19-acetoxy derivative has [] 26D +185o (CHCl3) and max 237.5nm in EtOH. [Ehrenstein & Dünnenberger J Org Chem 21 774 1956, Beilstein 8 IV2162.] |
| 19-HYDROXY-4-ANDROSTENE-3,17-DIONE Preparation Products And Raw materials |
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