2-HYDROXYCARBAZOLE
2-HYDROXYCARBAZOLE
  • CAS No.:86-79-3
Other grades of this product :
2-HYDROXYCARBAZOLE Basic information
Product Name:2-HYDROXYCARBAZOLE
Synonyms:AURORA KA-4595;2-HYDROXYCARBAZOLE;carbazol-2-ol;2-Hydroxycarbazol (9H-Carbazol-2-ol),;9H-CARBAZOL-2-OL;2-carbazolol;QS794 2-HYDROXYCARBAZOLE;2-Hydroxy-9H-carbazole
CAS:86-79-3
MF:C12H9NO
MW:183.21
EINECS:201-699-7
Product Categories:Intermediates of Dyes and Pigments;Nitrogen cyclic compounds;Building Blocks;Carbazoles;Chemical Synthesis;Heterocyclic Building Blocks
Mol File:86-79-3.mol
2-HYDROXYCARBAZOLE Chemical Properties
Melting point 270-273 °C (lit.)
Boiling point 316.88°C (rough estimate)
density 1.1261 (rough estimate)
refractive index 1.5880 (estimate)
pka10.05±0.30(Predicted)
BRN 135859
CAS DataBase Reference86-79-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,C,T,F
Risk Statements 36/37/38-34
Safety Statements 26-36-37/39-45-36/37/39-27
WGK Germany 2
RTECS FE6355000
HS Code 2933998090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
2-HYDROXYCARBAZOLE Usage And Synthesis
Chemical Propertiesbeige to light brown crystalline powder
UsesCarbazol has been found possible to distinguish between heparin, heparin derivatives, and other polyuronides of connective tissue. A new modification of the carbazole analysis is useful for determination of d-mannuronic acid in heteropolysaccharides. 2-Hydroxycarbazole was used in the synthesis of isochromene fused carbazol, (4aS,13bR)-2,5,5-trimethyl-3,4,4a,5,8,13b-hexahydroisochromeno[3,4-b]carbazole.
General Description2-Hydroxycarbazole is a compound structurally related to the Ca2+-mobilizing marine toxin, 9-methyl-7-bromoeudistomin. Room temperature electronic absorption and fluorescence spectra of 2-hydroxycarbazole has been studied in concentrated aqueous potassium hydroxide solutions. It undergoes chemoselective N-alkylation using NaH as a base in a THF-DMF solvent system.

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