4-Methoxypyridine
4-Methoxypyridine
  • CAS No.:620-08-6
Other grades of this product :
4-Methoxypyridine Basic information
Product Name:4-Methoxypyridine
Synonyms:gamma-Methoxypyridine;4-METHOXYPYRIDINE;METHYL PYRIDIN-4-YL ETHER;4-METHOXYPYRIDINE, 98+%;4-methoxypridine;Pyridine, 4-methoxy-;4-Methoxypyridine, 99% 5ML;4-Methoxypyridine,99%
CAS:620-08-6
MF:C6H7NO
MW:109.13
EINECS:210-624-7
Product Categories:C6;Heterocyclic Building Blocks;Pyridines, Pyrimidines, Purines and Pteredines;Pyridine series;Pyridine Derivertives;Boronic Acid;blocks;Pyridines;Pyridine
Mol File:620-08-6.mol
4-Methoxypyridine Chemical Properties
Melting point 4 °C
Boiling point 108-111 °C/65 mmHg (lit.)
density 1.075 g/mL at 25 °C (lit.)
refractive index 1.518-1.522
Fp 74 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Liquid
pka6.58(at 25℃)
Specific Gravity1.075
color Clear colorless to slightly yellow
BRN 108211
CAS DataBase Reference620-08-6(CAS DataBase Reference)
NIST Chemistry ReferencePyridine, 4-methoxy-(620-08-6)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 36/37/38-20/21/22
Safety Statements 37/39-26-36-36/37/39
WGK Germany 3
HS Code 29339900
MSDS Information
ProviderLanguage
ACROS English
ALFA English
4-Methoxypyridine Usage And Synthesis
Chemical Propertiesclear colorless to slightly yellow liquid
Uses4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors.
Uses4-Methoxypyridine was used as a starting reagent for the stereocontrolled synthesis of (±)-pumiliotoxin C and (±)-lasubine II. It was also used in an efficient construction of dihyropyridin-4-ones, which serves as potential ligands for neuronal nicotinic acetycholine receptors.
General Description4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied.

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