4-Chloro-3-(trifluoromethyl)phenyl isocyanate
4-Chloro-3-(trifluoromethyl)phenyl isocyanate
  • CAS No.:327-78-6
Other grades of this product :
4-Chloro-3-(trifluoromethyl)phenyl isocyanate Basic information
Product Name:4-Chloro-3-(trifluoromethyl)phenyl isocyanate
Synonyms:4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE;3-TRIFLUOROMETHYL-4-CHLORO-PHENYL ISOCYANATE;4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 98%;1-Chloro-4-isocyanato-2-(trifluoromethyl)benzene;4-Chloro-α,α,α-trifluoro-m-tolyl isocyanate;4-Chloro-3-(trifluoromethyl)phenyl isocyanate,98%;4-Chloro-3-(trifluoroMethyl)phenyl isocyanate, 98% 5GR;Benzene, 1-chloro-4-isocyanato-2-(trifluoromethyl)-
CAS:327-78-6
MF:C8H3ClF3NO
MW:221.56
EINECS:608-783-6;455-070-9
Product Categories:Phenyl isocyanate&Phenyl isothiocyanate;Isocyanates;Nitrogen Compounds;Organic Building Blocks
Mol File:327-78-6.mol
4-Chloro-3-(trifluoromethyl)phenyl isocyanate Chemical Properties
Melting point 40-42 °C(lit.)
Boiling point 86-90 °C14 mm Hg(lit.)
density 1.4720 (estimate)
vapor pressure 91Pa at 20℃
Fp 211 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form Low Melting Solid, Powder or Chunks
color White to yellow
Sensitive Moisture Sensitive
BRN 522032
InChIKeyAHFPRSSHNSGRCU-UHFFFAOYSA-N
CAS DataBase Reference327-78-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37-36/37/38-42-20/22
Safety Statements 7-26-27-37/39-36/37/39-45-23
RIDADR UN 2206 6.1/PG 3
WGK Germany 3
Hazard Note Harmful/Moisture Sensitive
HazardClass 6.1
PackingGroup III
HS Code 29291090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
4-Chloro-3-(trifluoromethyl)phenyl isocyanate Usage And Synthesis
Chemical PropertiesWhite solid or melt
Uses4-Chloro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of: N-(5′-deoxy-3′-O-tert-butyldimethylsilyl-β-D-thymidin-5′-yl)-N′-(4-chloro-3-trifluoromethylphenyl)-thiourea [1,3-bis(4-chloro-α,α,α-trifluoro-m-tolyl)urea] trans-1-(4-chloro-3-trifluoromethyl-phenyl)-3-(4-hydroxy-cyclohexyl)-urea
Uses4-Chloro-3-(trifluoromethyl)phenyl isocyanate may be used in the synthesis of:
  • N-(5′-deoxy-3′-O-tert-butyldimethylsilyl-β-D-thymidin-5′-yl)-N′-(4-chloro-3-trifluoromethylphenyl)-thiourea
  • [1,3-bis(4-chloro-α,α,α-trifluoro-m-tolyl)urea]
  • trans-1-(4-chloro-3-trifluoromethyl-phenyl)-3-(4-hydroxy-cyclohexyl)-urea
General Description4-Chloro-3-(trifluoromethyl)phenyl isocyanate participates in an efficient methodology for the synthesis of 5-methyl-3-aryl-2-thiooxazolidin-4-ones.
Flammability and ExplosibilityNonflammable
4-Chloro-3-(trifluoromethyl)phenyl isocyanate Preparation Products And Raw materials
Raw materials2-Chloro-5-nitrobenzotrifluoride-->4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine-->2-Chlorobenzotrifluoride
Preparation ProductsRegorafenib iMpurity

Welcome!

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

  • NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
  • +86-23-6139-8061 +86-13650506873
  • danny@chemdad.com sales@chemdad.com
  • www.chemdad.com
  • WhatsApp +86-13650506873

Name

phone

company

email

message

Google translate: 日本语 한국어 Français Deutsch España Türkiye