4-Fluoro-3-nitrobenzoic acid
4-Fluoro-3-nitrobenzoic acid
  • CAS No.:453-71-4
Other grades of this product :
4-Fluoro-3-nitrobenzoic acid Chemical Properties
Melting point 123-126 °C (lit.)
Boiling point 92°C 15mm
density 1.5071 (estimate)
Fp 92°C/15mm
storage temp. Sealed in dry,Room Temperature
solubility 95% ethanol: soluble50mg/mL, clear, light yellow
pka3.54±0.10(Predicted)
form Powder or Crystals
color Light yellow to tan
Water Solubility insoluble
BRN 2107562
CAS DataBase Reference453-71-4(CAS DataBase Reference)
NIST Chemistry Reference4-Fluoro-3-nitrobenzoic acid(453-71-4)
Safety Information
Hazard Codes Xn,Xi
Risk Statements 22-36/37/38
Safety Statements 26-36-24/25
WGK Germany 2
HazardClass IRRITANT
HS Code 29163990
MSDS Information
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4-Fluoro-3-nitrobenzoic acid English
ACROS English
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4-Fluoro-3-nitrobenzoic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses4-Fluoro-3-nitrobenzoic acid was used:
  • as starting reagent in the preparation of novel benzimidazoles having antimycobacterial activity
  • in preparation of series of novel acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors containing benzimidazole core structure
  • in preparation of bis(heterocyclic) skeletal precursors for the Pictet-Spengler reaction
  • in solid-phase synthesis of trisubstituted [1,3,5]triazino[1,2-a]benzimidazole-2,4(3H,10H)-diones

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