2-Fluoro-3-pyridylboronic acid
2-Fluoro-3-pyridylboronic acid
  • CAS No.:174669-73-9
Other grades of this product :

2-Fluoro-3-pyridylboronic acid Basic information
Product Name:2-Fluoro-3-pyridylboronic acid
Synonyms:2-Fluoropyridine-3-boronic acid,97%;3-Borono-2-fluoropyridine;2-Fluoropyridine-3-boronic Acid 2-Fluoropyridine-3-boronic Acid (contains varying aMounts of Anhydride);2-fluoropyridin-3-yl-3-boronic acid;2-Fluoro-3-pyridylboronic;(2-Fluoropyridin-3-yl)boronic acid hydrate;2-Fluoro-3-pyridylboronic acid   2-Fluoropyridine-3-boronic acid
CAS:174669-73-9
MF:C5H5BFNO2
MW:140.91
EINECS:
Product Categories:Boronate Ester;Potassium Trifluoroborate;PYRIDINE;HALIDE;blocks;Boronic Acids & Esters;BoronicAcids;Pyridines;Fluorinated;Organoborons;Boronic acid;Boronic  Acids  &  Esters;Boric acid series
Mol File:174669-73-9.mol
2-Fluoro-3-pyridylboronic acid Chemical Properties
Melting point 274-283 °C
Boiling point 322.6±52.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility soluble in Methanol
pka6.68±0.58(Predicted)
form solid
color white
BRN 9119935
CAS DataBase Reference174669-73-9(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
TSCA No
HazardClass IRRITANT
HS Code 29333990
MSDS Information
ProviderLanguage
ALFAEnglish
2-Fluoro-3-pyridylboronic acid Usage And Synthesis
Chemical PropertiesWhite powder
UsesReactant involved in:
  • Heterocyclization eith α-oxocarboxylic acids

  • Suzuki-Miyaura coupling reactions

Additionally used as a precursor to biologically active molecules including:
  • Heteroaryl benzylureas with glycogen synthase kinase 3 inhibitory activity

  • Carboxyindoles with HCV NS5B polymerase inhibitory activity

  • Pyrazolyl- and thienyl-aminohydantoins with BACE1 inhibitory activity

2-Fluoro-3-pyridylboronic acid Preparation Products And Raw materials
Raw materialsDiethyl ether-->Nitrogen-->Triisopropyl borate-->Lithium diisopropylamide-->2-Fluoropyridine

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