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| (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Basic information |
| Product Name: | (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate | | Synonyms: | ATS-8;(4R,6R)-T-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R,6R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R,CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R,3R)-TERT-BUTYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;(4R-CIS)-1,1-DIMETHYLETHYL-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-8);tert-Butyl (4R,3R)-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate;TERT-BUTYL[(4R,6R)-6-CYANOMETHYL-2,2-DIMETHYL-1,3-DIOXAN-4-YL]ACETATE | | CAS: | 125971-94-0 | | MF: | C14H23NO4 | | MW: | 269.34 | | EINECS: | 425-780-3 | | Product Categories: | INTERMEDIATESOFATORVASTATIN;chiral;Chemical intermediate for Atorvastatin Calcium;(intermediate of atorvastatin);Chiral Building Blocks;Atorvastatin intermediates;Cyanides/Nitriles;Organic Building Blocks | | Mol File: | 125971-94-0.mol |
| (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties |
| Melting point | 65-69 °C(lit.) | | Boiling point | 364.1±17.0 °C(Predicted) | | density | 1.016±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | soluble in Chloroform | | form | powder to crystal | | color | White to Almost white | | optical activity | [α]20/D 1.0°, c = 1 in chloroform | | CAS DataBase Reference | 125971-94-0(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | HS Code | 29329990 |
| (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Atorvastatin Intermediate | | Uses | (4R,6R)-6-(Cyanomethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester is an intermediate of Atorvastatin (A791750, Ca salt), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia. |
| (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials |
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