Other grades of this product :
| Mepivacaine hydrochloride Basic information |
| Product Name: | Mepivacaine hydrochloride | | Synonyms: | Mepivacaine Hydrochloride (200 mg);Ropivacaine base Mepivacaine HCL;(1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride;1-methyl-2’,6’-pipecoloxylididehydrochloride;Mepivacaine HCl USP;2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride;2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI);2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI) | | CAS: | 1722-62-9 | | MF: | C15H22N2O.ClH | | MW: | 282.81 | | EINECS: | 217-023-9 | | Product Categories: | API;Sodium channel;Amines;Aromatics;Heterocycles;Analgesic series;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 1722-62-9.mol |
| Mepivacaine hydrochloride Chemical Properties |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 22-24/25 | | RIDADR | UN 2811 6.1 / PGIII | | RTECS | TK6475000 | | HS Code | 29333990 | | Toxicity | LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) |
| Mepivacaine hydrochloride Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | anesthetic (local) | | Uses | Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography. | | Uses | An anti-inflammatory and analgesic | | Definition | ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic. | | Brand name | Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco). | | Biological Functions | Mepivacaine hydrochloride (Carbocaine) is longer
acting than lidocaine and has a more rapid onset of action
(3–5 minutes). Topical application is not effective.
It has been widely used in obstetrics, but its use has declined
recently because of the early transient neurobehavioral
effects it produces. Adverse reactions associated
with mepivacaine are generally similar to those
produced by other local anesthetics. It can be used with
epinephrine or levonordefrin (dental use only). | | General Description | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc. | | Biochem/physiol Actions | Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems. | | Safety Profile | skin irritant. Questionable carcinogen with |
| Mepivacaine hydrochloride Preparation Products And Raw materials |
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