Methyl 6-bromo-2-naphthoate
Methyl 6-bromo-2-naphthoate
  • CAS No.:33626-98-1
Other grades of this product :
Methyl 6-bromo-2-naphthoate Basic information
Product Name:Methyl 6-bromo-2-naphthoate
Synonyms:6-Bromo-2-Naphtoic Acid Methyl Ester;2-Bromo-6-naphthoic acid methylester;6-BROMO-2-NAPHTHALENECARBOXYLIC ACID METHYL ESTER;6-BROMO-2-NAPHTHOIC ACID METHYL ESTER;METHYL 6-BROMO-2-NAPHTHALENECARBOXYLATE;METHYL 6-BROMO-2-NAPHTHOATE;2-Naphthoic acid, 6-bromo, methyl ester;Methyl-6-bromo-2-naphtoate
CAS:33626-98-1
MF:C12H9BrO2
MW:265.1
EINECS:608-896-0
Product Categories:Naphthalene series;Building Blocks;C12 to C63;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks;Aromatic Esters;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Intermediates of Adapalene;C12 to C63;Carbonyl Compounds;Esters;API;Others chemical reagents;blocks;Bromides;Carboxes;ADAPALENE
Mol File:33626-98-1.mol
Methyl 6-bromo-2-naphthoate Chemical Properties
Melting point 123-126 °C (lit.)
Boiling point 357.0±15.0 °C(Predicted)
density 1.492±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), DMSO (Slightly)
form Crystalline Powder
color Off-white to cream or light brown
BRN 2578943
InChIKeyJEUBRLPXJZOGPX-UHFFFAOYSA-N
CAS DataBase Reference33626-98-1(CAS DataBase Reference)
Safety Information
Hazard Codes C
Risk Statements 20/21/22-34
Safety Statements 24/25-45-36/37/39-27-26
WGK Germany 3
HS Code 29163990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Methyl 6-bromo-2-naphthoate Usage And Synthesis
Chemical PropertiesPale yellow or light brown powder
UsesMethyl 6-Bromo-2-napthoate is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.
UsesMethyl 6-Bromo-2-napthoate (Adapalene USP Related Compound A) is used in the synthesis of Adapalene, a retinoid specific for RARβ and RARγ receptors.
UsesMethyl 6-bromo-2-naphthoate may be used to synthesize:
  • 6-vinyl-2-naphthalencarbaldehyde
  • methyl 6-(3-tert-butyl-4-methoxyphenyl)-2-naphthoate
  • methyl 6-[3-tert-butyl-4-[(tert-butyldiethylsilyl)oxy]-phenyl]-2-naphthoate
  • methyl 6-[3-(1-adamantyl)-4-[(tert-butyldimethylsilyl)-oxy]phenyl]-2-naphthoate
  • methyl 6-[3-(1-adamantyl)-4-[[(2,3-dimethyl-1,3-dioxolan-4-yl)methylloxy]phenyl]-2-naphthoate
  • 2-bromo-6-(bromomethyl)naphthalene
General DescriptionMethyl 6-bromo-2-naphthoate undergoes aromatic Finkelstein reaction followed by hydrolysis to afford 6-iodo-2-naphthoic acid.
Methyl 6-bromo-2-naphthoate Preparation Products And Raw materials
Preparation Products2,2'-Bis-(1-adaMantyl)-4,4'-diMethoxybiphenyl-->2-Acetyl-6-bromonaphthalene

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