Other grades of this product :
| (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Basic information | | Uses |
| Product Name: | (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat | | Synonyms: | (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat;Telotristat;(2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid;LP 778902;LP-778902/ Telotristat;(S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoicacid;Telotristat, LP778902;Telotrisalt | | CAS: | 1033805-28-5 | | MF: | C25H22ClF3N6O3 | | MW: | 546.93 | | EINECS: | | Product Categories: | | Mol File: | 1033805-28-5.mol |
| (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Chemical Properties |
| Boiling point | 731.1±70.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | solubility | ≥27.35 mg/mL in DMSO with ultrasonic; insoluble in H2O; insoluble in EtOH | | pka | 2.04±0.10(Predicted) |
| (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Usage And Synthesis |
| Uses | Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor. | | Uses | Telotristat acts as a tryptophan hydroxylase (TPH) inhibitor. | | Biological Activity | telotristat is the active metabolite of lx1606(telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (tph) inhibitor with potential antiserotonergic activity. |
| (2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat Preparation Products And Raw materials |
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![(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat](/img/1033805-28-5.jpg "(2S)-2-aMino-3-[4-[2-aMino-6-[(1R)-1-[4-chloro-2-(3-Methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyriMidin-4-yl]phenyl]propanoic acid, Telotristat")
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