(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
  • CAS No.:156928-09-5
Other grades of this product :

(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Basic information
Product Name:(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol
Synonyms:(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol;(3R, 3aS, 6aS)-hexahydrofuro[2,3-b]furan-3-ol;(3R)-hexahydrofuro[2,3-b]furan-3-ol;3-hydroxy-(3R,3αS,6αR)-bis-tetrahydrofuran;Furo[2,3-b]furan-3-ol, hexahydro-, (3R,3aS,6aR;HEXAHYDRO-(3R,3AS,6AR)-FURO(2,3-B)FURAN-3-OL;(3R,3aS,6aR);3-hydroxy-(3R,3±S,6±R)-bis-tetrahydrofuran
CAS:156928-09-5
MF:C6H10O3
MW:130.14
EINECS:605-076-4
Product Categories:
Mol File:156928-09-5.mol
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Chemical Properties
Boiling point 251.5±20.0 °C(Predicted)
density 1.275
vapor pressure 0.19Pa at 25℃
storage temp. 2-8°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly, Heated)
pka14.07±0.20(Predicted)
form Oil
color Pale Yellow
LogP1.055 at pH5
Safety Information
MSDS Information
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Usage And Synthesis
Uses(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol is used as a reagent in the synthesis of Darunavir (D193500); a second generation HIV-1-protease inhibitor and antiviral agent.
(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-ol Preparation Products And Raw materials
Raw materials2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-ol-->2-Furanol, 3-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]tetrahydro-, (3S)--->809286-93-9-->(3S,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol-->Vinyl acetate
Preparation Products(3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ol

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