2-Amino-6-methylpyrazine Six Chongqing Chemdad Co. ，Ltd

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2-Amino-6-methylpyrazine

CAS No.：5521-56-2

Other grades of this product :

2-Amino-6-methylpyrazine Basic information

Product Name:	2-Amino-6-methylpyrazine
Synonyms:	2-AMINO-6-METHYLPYRAZINE;2-Amino-6-methylpyrazine 97%;2-AMINE-6-METHYLPYRAZINE;6-METHYLPYRAZIN-2-AMINE;6-METHYLPYRAZIN-2-YLAMINE;6-Methyl-2-pyrazinamine;6-Methylpyrazin-2-amine, 2-Amino-6-methyl-1,4-diazine;2-Amino-6-methylpyrazine97%
CAS:	5521-56-2
MF:	C5H7N3
MW:	109.13
EINECS:	691-008-9
Product Categories:	Piperazine series;Amines;Pyrazines, Pyrimidines & Pyridazines;Imidazoles & Benzimidazoles;Imidazoles & Benzimidazoles;Pyrazines, Pyrimidines & Pyridazines
Mol File:	5521-56-2.mol

2-Amino-6-methylpyrazine Chemical Properties

Melting point	122.0 to 126.0 °C
Boiling point	246.0±35.0 °C(Predicted)
density	1.155±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
form	Solid
pka	3.52±0.10(Predicted)
color	White to Yellow to Orange
CAS DataBase Reference	5521-56-2

Safety Information

Hazard Codes	Xi,Xn
Risk Statements	22
Hazard Note	Irritant
HS Code	2933998090

MSDS Information

2-Amino-6-methylpyrazine Usage And Synthesis

Uses	6-Methylpyrazin-2-amine is used in the preparation of heterocyclic amides containing pyridyl sulfones as TYK-2 signaling inhibitors useful in treatment of inflammatory and autoimmune diseases.

2-Amino-6-methylpyrazine Preparation Products And Raw materials

Raw materials

Dimethyl 2-(6-chloropyrazin-2-yl)malonate hydrochloride-->2-Chloro-6-methylpyrazine-->Pyrazinecarboxylic acid, 3-amino-5-methyl- (7CI,8CI,9CI)-->METHYLZINC CHLORIDE-->2-AMINO-3,5-DIBROMO-6-METHYLPYRAZINE-->(6-CHLOROPYRAZIN-2-YL)ACETIC ACID-->2-HYDROXY-6-METHYLPYRAZINE-->7-methyllumizine-->2-Chloro-6-aminopyrazine-->Methylmagnesium Bromide-->DIMETHYLZINC

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