Other grades of this product :
| ACRIFLAVINE Basic information |
| Product Name: | ACRIFLAVINE | | Synonyms: | 2,8-DIAMINO-10-METHYLACRIDINIUM CHLORIDE;Acriflavine 10;Trypaflavine Neutral;GUANOSINE ULTRA PURE GRADE;4-Acetamino phenol ( APAP );Acriflavine 〔Trypaflavine〕;Acriflavine, 95%, mixture of 3,6-Diamino-10-methylacridinium Chloride and 3,6-Diaminoacridine;XANTHACRIDINE | | CAS: | 8048-52-0 | | MF: | C27H25ClN6 | | MW: | 468.98 | | EINECS: | 999-999-2 | | Product Categories: | marker | | Mol File: | 8048-52-0.mol |
| ACRIFLAVINE Chemical Properties |
| Melting point | 179-181 °C | | Boiling point | 612.69°C (rough estimate) | | density | 1.0933 (rough estimate) | | refractive index | 1.6000 (estimate) | | solubility | H2O: soluble0.33g/mL (lit.)(lit.) | | form | Powder | | color | Deep orange to brownish-red | | Merck | 14,123 | | CAS DataBase Reference | 8048-52-0(CAS DataBase Reference) | | EPA Substance Registry System | Xanthacridinum (8048-52-0) |
| ACRIFLAVINE Usage And Synthesis |
| Chemical Properties | Acriflavine hydrochloride is deep orange to brownish-red powder
| | Uses | Acriflavine is used in applications for dual fluorescence analysis of cellular DNA and protein simultaneously.
| | Uses | Fluorescent label for high molecular weight RNA | | Safety Profile | Poison by
subcutaneous route. Questionable
carcinogen with experimental tumorigenic
data. Human mutation data reported. A
topical antiseptic used in the treatment of
gonorrhea. When heated to decomposition
it emits very toxic fumes of NOx and Cl-.
See also 3,6-DIAMINO-10
METHYLACRIDINIUM CHLORIDE. | | Purification Methods | Treat acriflavin twice with freshly precipitated AgOH to remove proflavine, then recrystallise it from absolute methanol [Wen & Hsu J Phys Chem 66 1353 1962]. [Beilstein 22 III/IV 218.] |
| ACRIFLAVINE Preparation Products And Raw materials |
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