2-Amino-5-fluorobenzoic acid
2-Amino-5-fluorobenzoic acid
  • CAS No.:446-08-2
Other grades of this product :
2-Amino-5-fluorobenzoic acid Basic information
Product Name:2-Amino-5-fluorobenzoic acid
Synonyms:2-AMINO-5-FLUOROBENZOIC ACID;RARECHEM AL BO 2236;2-AMino-5-fluorobenzoic acid, 97% 1GR;NSC 513308;2-aMino-5-fluorobenzoic aicd;2-Amino-5-fluorobenzoic acid 98%;5-Fluoroanthranilic acid, 2-Carboxy-4-fluoroaniline;Anthranilic acid, 5-fluoro-
CAS:446-08-2
MF:C7H6FNO2
MW:155.13
EINECS:207-159-7
Product Categories:Aromatics;5-FOA;Nucleotides and Nucleosides;Benzoic acid Series;Bases & Related Reagents;Nucleotides;FINE Chemical & INTERMEDIATES;Fluorobenzene;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Aromatics Compounds;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid series;Amines;Fluorin-contained Benzoic acid series;Carboxylic Acids;Phenyls & Phenyl-Het;Benzoic acid;Fluorine series
Mol File:446-08-2.mol
2-Amino-5-fluorobenzoic acid Chemical Properties
Melting point 181-183 °C(lit.)
Boiling point 223.67°C (rough estimate)
density 1.3021 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
pka1.86±0.10(Predicted)
form Fine Crystalline Powder
color Light yellow to light brown
BRN 2803664
InChIKeyFPQMGQZTBWIHDN-UHFFFAOYSA-N
CAS DataBase Reference446-08-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,T
Risk Statements 36/37/38
Safety Statements 26-36-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29224999
MSDS Information
ProviderLanguage
5-Fluoroanthranilic acid English
ACROS English
SigmaAldrich English
ALFA English
2-Amino-5-fluorobenzoic acid Usage And Synthesis
Chemical Propertieswhite to light yellow crystal powder
Uses2-Amino-5-fluorobenzoic acid is used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs.
UsesUsed in the synthesis of styrylquinazolinones which are potential anticancer agents.
DefinitionChEBI: An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.

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