FMOC-5-AMINOPENTANOIC ACID
FMOC-5-AMINOPENTANOIC ACID
  • CAS No.:123622-48-0
Other grades of this product :
FMOC-5-AMINOPENTANOIC ACID Basic information
Product Name:FMOC-5-AMINOPENTANOIC ACID
Synonyms:FMOC-5-AMINOVALERIC ACID;FMOC-5-AVA-OH;FMOC-5-AMINOPENTANOIC ACID;FMOC-NH-(CH2)4-COOH;FMOC-APE(5)-OH;RARECHEM EM WB 0074;N-(9-FLUORENYLMETHYLOXYCARBONYL)-5-AMINO-PENTANOIC ACID;5-(FMOC-AMINO)PENTANOIC ACID
CAS:123622-48-0
MF:C20H21NO4
MW:339.39
EINECS:
Product Categories:Amino Acids
Mol File:123622-48-0.mol
FMOC-5-AMINOPENTANOIC ACID Chemical Properties
Melting point 135-136 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3))
Boiling point 575.8±33.0 °C(Predicted)
density 1.232±0.06 g/cm3(Predicted)
storage temp. 2-8°C
form Powder
pka4.71±0.10(Predicted)
color White
BRN 3565625
CAS DataBase Reference123622-48-0
Safety Information
Safety Statements 24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29242990
MSDS Information
ProviderLanguage
SigmaAldrich English
FMOC-5-AMINOPENTANOIC ACID Usage And Synthesis
DescriptionFmoc-5-aminopentanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical PropertiesWhite powder
Uses5-(Fmoc-amino)valeric acid is used as pharmaceutical intermediate.
UsesFmoc-5-aminopentanoic acid, tech grade

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