Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Six Chongqing Chemdad Co. ，Ltd

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Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate

CAS No.：148901-69-3

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Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Basic information

Product Name:	Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate
Synonyms:	ETHYL (E)-7-[4-(4''-FLUOROPHENYL)-2-(CYCLOPROPYL)-3-QUINOLINYL]-5-HYDROXY-3-OXO-6-HEPTENOATE; (S,E)-ethyl 7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl);Ethyl (E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate;Pitavastatin 3-Oxo Ethyl Ester;(E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic acid ethyl ester;3-Oxo Pitavastatin Ethyl Ester;Ethyl (5S, 6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3-quinolinyl] -5-hydroxy-3-oxo-6-heptenoate;Ethyl(E)-(5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-5-hydroxy-3-oxo-3-quinolinyl]-hept-6-enoate
CAS:	148901-69-3
MF:	C27H26FNO4
MW:	447.5
EINECS:	604-664-8
Product Categories:
Mol File:	148901-69-3.mol

Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Chemical Properties

Boiling point	651.3±55.0 °C(Predicted)
density	1.268
storage temp.	Sealed in dry,Room Temperature
pka	10.30±0.46(Predicted)
CAS DataBase Reference	148901-69-3(CAS DataBase Reference)

Safety Information

MSDS Information

Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Usage And Synthesis

Uses	(E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Ethyl Ester is an impurity of Pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase and antilipemi c agent.
Uses	(E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Ethyl Ester is an impurity of Pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase and antilipemic agent.

Ethyl (E)-7-[4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoate Preparation Products And Raw materials

Raw materials

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol-->Methyl 3-cyclopropyl-3-oxopropionate-->2-Amino-4'-fluorobenzophenone-->(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-2-propenenitrile-->Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate-->(E)-3-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl-2-propenal-->2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carboxaldehyde-->Ethyl acetoacetate

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