Fluoroacetonitrile
Fluoroacetonitrile
  • CAS No.:503-20-8
Other grades of this product :
Fluoroacetonitrile Basic information
Product Name:Fluoroacetonitrile
Synonyms:Fluoromethyl cyanide;FLUOROACETONITRILE;Acetonitrile, fluoro-;fluoro-acetonitril;Floroacetonitrile;monofluoroacetonitrile;Fluoroacetonitrile,99%;2-fluoroacetonitrile
CAS:503-20-8
MF:C2H2FN
MW:59.04
EINECS:
Product Categories:C1 to C5;Cyanides/Nitriles;Nitrogen Compounds
Mol File:503-20-8.mol
Fluoroacetonitrile Chemical Properties
Melting point -13 °C
Boiling point 79-80 °C (lit.)
density 1.061 g/mL at 25 °C (lit.)
refractive index 1.333
Fp 7°F
Water Solubility Slightly soluble in water
form clear liquid
color Colorless to Almost colorless
CAS DataBase Reference503-20-8(CAS DataBase Reference)
NIST Chemistry ReferenceFluoroacetonitrile(503-20-8)
Safety Information
Hazard Codes F;T,T,F
Risk Statements 11-23/24/25-36/37/38
Safety Statements 16-26-27-36/37/39-45
RIDADR UN 3273
WGK Germany 3
RTECS AM0175000
HazardClass 3.1
PackingGroup II
HS Code 2926907090
MSDS Information
Fluoroacetonitrile Usage And Synthesis
UsesFluoroacetonitrile is a water disinfectant byproduct that showed weak inhibition of rat hepatic glutathione S-transferases in vitro. Fluoroacetonitrile is also a reagent in the preparation of the PAD4 inhibitor F-Amidine.
UsesFluoroacetonitrile has been used in preparation of:
  • 2-fluoromethyl-4,4,6-trimethyl-1,3-oxazine
  • α-fluorinated acetophenone
  • 2-amino-2-fluoromethyl-3-pentenenitrile, a key intermediate in the synthesis of 2,5-diamino-2-fluoromethyl-3(E)-pentenoic acid
Synthesis Reference(s)Journal of Medicinal Chemistry, 26, p. 1551, 1983 DOI: 10.1021/jm00365a002
Fluoroacetonitrile Preparation Products And Raw materials
Preparation Products2'-FLUOROACETOPHENONE-->FLUOROACETAMIDE

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