| Hydroxysafflor yellow A Basic information |
| Product Name: | Hydroxysafflor yellow A |
| Synonyms: | SAFFLOMIN A;Hydroxysafflor yellow A;2,5-Cyclohexadien-1-one, 2,4-di-beta-D-glucopyranosyl-3,4,5-trihydroxy-6-((2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl)-;Hydroxysafflor yellow A,SaffloMin A,HSYA;Hydroxysafflor yellow A,Safflomin A;Hydroxysafflor yellow;Safflomin A, 98%, from Carthamus tinctorius L.;HSYA |
| CAS: | 78281-02-4 |
| MF: | C27H32O16 |
| MW: | 612.54 |
| EINECS: | |
| Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol File: | 78281-02-4.mol |
| Hydroxysafflor yellow A Chemical Properties |
| Melting point | 184-186 °C |
| Boiling point | 1015.8±65.0 °C(Predicted) |
| density | 1.851±0.06 g/cm3(Predicted) |
| pka | 4.50±1.00(Predicted) |
| Safety Information |
| Safety Statements | 24/25 |
| HS Code | 29389090 |
| MSDS Information |
| Hydroxysafflor yellow A Usage And Synthesis |
| Biological Activity | Hydroxysafflor yellow A is a pigment that has been found in C. tinctorius and has diverse biological activities. It inhibits LPS-induced increases in NF-κB levels and production of nitric oxide (NO), IL-1β, and TNF-α in primary mouse embryonic mesencephalic cultures when used at concentrations of 40 and 160 μM. |
| in vivo | Hydroxysafflor yellow A (1 and 3 mg/kg) decreases mean arterial pressure (MAP) and heart rate in anesthetized normotensive or spontaneously hypertensive rats. It reduces infarct volume and serum superoxide dismutase (SOD) activity in a rat model of focal transient cerebral is chemia induced by middle cerebral artery occlusion (MCAO) when administered at doses of 2, 4, and 8 mg/kg. |
| Hydroxysafflor yellow A Preparation Products And Raw materials |
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