2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
  • CAS No.:24522-30-3
Other grades of this product :
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Basic information
Product Name:2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide
Synonyms:2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide;AcetaMide, 2-cyano-N-[4-(trifluoroMethyl)phenyl]-;Leflunomide Impurity H;Leflunomide EP Impurity H;Leflunomide Impurity 8(Leflunomide EP Impurity H);2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide;2-Cyano-N-[4-(trifluoromethyl)pheny;2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide USP/EP/BP
CAS:24522-30-3
MF:C10H7F3N2O
MW:228.17
EINECS:
Product Categories:
Mol File:24522-30-3.mol
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Chemical Properties
Melting point 145-147℃
Boiling point 386.3±42.0 °C(Predicted)
density 1.375±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka4.63±0.10(Predicted)
color White to Off-White
Stability:Hygroscopic
Safety Information
HS Code 2924297099
MSDS Information
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Usage And Synthesis
Uses2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2.
2-cyano-N-[4-(trifluoromethyl)phenyl]acetamide Preparation Products And Raw materials
Raw materials1-CYANOACETYL-3,5-DIMETHYLPYRAZOLE-->Acetyl chloride, cyano--->Ethyl cyanoacetate-->Cyanoacetic acid-->4-Aminobenzotrifluoride

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