3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine
3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine
  • CAS No.:1034301-08-0
Other grades of this product :

3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine Basic information
Product Name:3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine
Synonyms:4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one;3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine;Decitabine Intermediate CR;1,3,5-Triazin-2(1H)-one,4-amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-b-D-erythro-pentofuranosyl]-;Decitabine Impurity 36;Decitabine Related Compound B;3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine;3',5'-Bis-O-(4-chlorobenzoyl)-2-deoxy-5-azacytosine   4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-beta-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
CAS:1034301-08-0
MF:C22H18Cl2N4O6
MW:505.31
EINECS:816-382-4
Product Categories:
Mol File:1034301-08-0.mol
3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine Chemical Properties
Melting point >182°C (dec.)
Boiling point 642.6±65.0 °C(Predicted)
density 1.58
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Very Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka3.38±0.20(Predicted)
color White
Safety Information
MSDS Information
3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine Usage And Synthesis
Uses4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (Decitabine USP Related Compound B) is a derivative of β-Decitabine (A796950) which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.
3',5'-di-o-p-chlorobenzoyl-2-deoxy-5-azacytosine Preparation Products And Raw materials
Raw materials1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose-->1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose-->4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one-->2-Deoxy-D-ribose-->N-(Trimethylsilyl)-4-[(trimethylsilyl)oxy]-2-amine-1,3,5-triazin

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