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1-ACETYLINDOLINE Basic information |
1-ACETYLINDOLINE Chemical Properties |
Melting point | 102-104 °C(lit.) | Boiling point | 125-130 °C(Press: 1 Torr) | density | 1.144±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | pka | 1.13±0.20(Predicted) | CAS DataBase Reference | 16078-30-1(CAS DataBase Reference) |
Safety Statements | 22-24/25 | WGK Germany | 3 | RTECS | NM1892500 | HS Code | 2933998090 |
1-ACETYLINDOLINE Usage And Synthesis |
Uses | • ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5 | Uses | 1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone. | Uses | - Reactant for preparation of triazolothiadiazepine dioxide derivatives
- Reactant for preparation of halo-substituted aromatic amides
- Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
- Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
- Reactant for regioselective ortho Suzuki-Miyaura coupling reaction
| Synthesis Reference(s) | Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1 | General Description | 1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported. |
1-ACETYLINDOLINE Preparation Products And Raw materials |
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